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Faculty Detail    
Name MARISA MARQUES
 
Campus Address WP P230 Zip 7331
Phone  205-934-6421
E-mail  mmarques@uab.edu
Other websites UAB Coagulation Service
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pathology   Laboratory Medicine Professor
Secondary  Diag & Thx Sci Chair (Org Ret)  Clin Lab Sci Div (Org Ret) Assistant Professor

Graduate Biomedical Sciences Affiliations
Molecular and Cellular Pathology Program 

Biographical Sketch 
I received my M.D. degree from the Federal University of Rio Grande do Sul in Brazil, followed by residency in Internal Medicine at the same institution. I moved to the United States with my husband in 1986 to become a Research Fellow at the National Institutes of Health in Bethesda, Maryland, for 2 years. We then moved to Boston, where I continued working as a fellow at Harvard Medical School. In 1993, we relocated to Birmingham, Alabama. I completed a residency in Pathology and a fellowship in Hematopathology at UAB and am Board certified in Anatomic and Clinical Pathology, with subspecialties in Hematology and Transfusion Medicine/Blood Banking. I am currently an Associate Professor of Pathology at UAB, serving as Head for Hemostasis and Transfusion Medicine sections. In addition, I am Laboratory Director of the Immunocytopenia, Anesthesia and CICU laboratories. My main focus is patient care, teaching and administrative oversight of these laboratories. In the clinical arena, I am particularly interested in improving appropriateness of utilization and interpretation of laboratory tests used in the investigation and management of bleeding and thrombotic disorders. Along with the technologists staffing the Hemostasis laboratory, we provide clinical consultation as the UAB Coagulation Service (http://uabcoag.net). Since last year, I am developing a blood management program at UAB along with the Blood Utilization and Management Committee and many other colleagues from across the institution.

Society Memberships
Organization Name Position Held Org Link
Academy of Clinical Laboratory Physicians and Scientists (ACLPS)    http://depts.washington.edu/lmaclps 
American Association of Blood Banks    www.aabb.org 
American Society of Apheresis (ASFA)    www.apheresis.org 
American Society of Clinical Pathologists (ASCP)    www.ascp.org 
American Society of Hematology (ASH)    www.hematology.org 
College of Amercan Pathologists (CAP)    www.cap.org 
International Society on Thrombosis and Haemostasis    www.med.unc.edu/isth/ 

Research/Clinical Interest
Title
Description
I am interested in various aspects of clinical research in the fields of coagulation and transfusion medicine. Since UAB is a center of reference for apheresis, we receive patients from throughout Alabama and neighboring states to be treated here for thrombotic thrombocytopenic purpura (TTP). In the last several years, I have been involved in several projects about TTP as seen in my list of publications. Other areas of interest in Transfusion Medicine include the effect of storage time on the red blood cells and the repercussion for the patients, as well as transfusion-related acute lung injury (TRALI). In the area of coagulation, I have an interest in hypercoagulability, heparin-induced thrombocytopenia diagnosis, and cost-effective utilization of laboratory assays.

Selected Publications 
Publication PUBMEDID
Passiment E, Meisel JL, Fontanesi J, Fritsma G, Aleryani SL, Marques M. Decoding laboratory test names: A major challenge to appropriate patient care. J Gen Inter Med 2013;28:453-8.   23192446 
Goyal J, Reddy VB, Marques MB. Acquired von Willebrand’s disease in myelofibrosis and essential Thrombocythemia. Haemophilia 2013;19:e256-7.  23590694 
Scott J, McCleskey B, Adamski J, and Marques MB. Thrombotic thrombocytopenic purpura does not show seasonal variation in Alabama. Transfusion 2013;53:1864-5.   23927642 
Goyal J, Adamski J, Lima JO, Marques MB. Relapses of thrombotic thrombocytopenic purpura after treatment with rituximab. J Clin Apher 2013;28:390-4.  23857472 
Hu X, Patel RP, Weinberg JA, Stapley R, Marques MB, Barnum SR. The level of complement activation fragments is higher in red blood cell units than segments. Transfus Apher Sci 2013;49:692-3.  24189461 
Sarode R, Bandarenko N, Brecher ME, Kiss JE, Marques MB, Szczepiorkowski ZM, Winters JL. Thrombotic thrombocytopenic purpura: 2012 American Society for Apheresis (ASFA) consensus conference on classification, diagnosis, management, and future research. J Clin Apher 2014; 29:148-67.  24136342 
Boone JD, Kim KH, Marques MB, Straughn JM. Compliance rates and outcomes associated with a restrictive transfusion policy in gynecologic oncology patients. Gynecol Oncol 2014;132:227-30.  24512847 
Oliver JC, Griffin RL, Hannon T, Marques MB. The success of our patient blood management program depended on an institution-wide change in transfusion practices. Transfusion 2014;54(10 Pt 2):2617-24.  24410741 
Hu X, , Patel RP, Weinberg J, Marques MB, Ramos TN, Barnum SR. Membrane Attack Complex Generation Increases as a Function of Time in Stored Blood. Transf Med 2014;24:114-6.   24588971 
Carlo W, Kirklin JK, Pearce FB, Marques MB, Adamski J, George JF. Single center experience with extracorporeal photopheresis in pediatric heart transplantation. J Heart Lung Transpl 2014; 33:624-8.  24661684 
Marques MB, Adamski J. Extracorporeal photopheresis: Technique, established and novel indications. J Clin Apher 2014;29:228-34.  24828404 
Marques MB, Singh N, Reddy VV. Out with the bad and in with the good; red cell exchange, white cell reduction, and platelet reduction. J Clin Apher 2014;29:220-7.   24828305 
Vetter TR, Adhami L, Porterfield J, Marques MB. Perceptions about blood transfusion: A survey of surgical patients and their anesthesiologists and surgeons. Anest Analg 2014;118:1301-8.   24842177 
Marques MB, Balogun RA. Therapeutic apheresis academy: Beyond borders. J Clin Apher 2014;29:189-90.  24864042 
Singh N, Vanlandingham S, Halverson C, Marques MB, Tallaj J, Kirklin J, Adamski J. Therapeutic plasma exchange rapidly improves cardiac allograft function in patients with presumed antibody-mediated rejection. J Clin Apher 2014;29:316-21.   24891048 
Marques MB, Wille KM, Ren Z, Sheth M, McGiffin DC. Successful pulmonary thromboendarterectomy in a patient with sickle cell disease treated with a single pre-operative red cell exchange. Transfusion 2014;54:1901-2.   25041151 
Williams LA, Hunter JM, Marques MB, Vetter TR. Periprocedural management of patients on anticoagulants. N Am Clin Lab Med 2014; 34:595-611.   25168945 
Vetter TR, Short RT, Hawn MT, Marques MB. Perioperative management of the patient with a coronary artery stent. Anesthesiology 2014;121:1093-8.   25211171 
Marques MB, Hickner J, Thompson PJ, Taylor JR. Primary care physicians and the laboratory: now and the future. Am J Clin Pathol 2014;142:738-40.   25389325 
Eichbaum Q, Smid WM, Crookes R, Naim N, Mendrone A Jr, Marques JF Jr, Marques MB. Apheresis in developing countries around the world. J Clin Apher 2014 Oct 27. doi: 10.1002/jca.21368. [Epub ahead of print].   25346394 
Limdi N, Nolin T, Booth S, Centi A, Marques MB, Crowley M, Allon M, Beasley T. Influence of kidney function on risk of supra-therapeutic INR related hemorrhage in warfarin users: A prospective warfarin cohort study. Am J Kidney Dis 2014 Nov 25. pii: S0272-6386(14)01377-8. doi: 10.1053. [Epub ahead of print].  25468385 
Dasararaju R, Marques MB. Adverse effects of transfusion. Cancer Control 2015;22:16-25.  25504275 
Harper V, Oh JW, Stapley R, Marques MB, Wilson L, Barnes S, Sun CW, Townes T, Patel RP. Peroxiredoxin-2 recycling is inhibited during erythrocyte storage. Antioxid Redox Signal 2015 Feb 1;22(4):294-307.   25264713 

Keywords
Thrombotic thrombocytopenic purpura (TTP), blood management