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Faculty Detail    
Name ONA MARIE FAYE-PETERSEN
 
Campus Address NP 3547 Zip 6823
Phone 205-975-8880
E-mail onafp@uab.edu
Other websites
     

Education
Medical School  University of Colorado School of Medicine    1980  M.D. 
Residency  Presbyterian/St. Luke's Medical Center    1982  Pathology 
Residency  Presbyterian/St. Luke's Medical Center    1985  Anatomic Clinical Pathology 
Fellowship  Memorial Sloan-Kettering Guttman Diagnostic Center    1986  Surgical Pathology 
Fellowship  Mount Sinai Hospital    1987  Pediatric Pathology 

Certifications
Diplomate, National Board of Medical Examiners   1982 
American Board of Pathology, Anatomic and Clinical Pathology  1987 
American Board of Pathology, Special Qualification in Pediatric Pathology  1991 
American Board of Pathology, Anatomic and Clinical Pathology - Recertification  2013 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pathology   Anatomic Pathology Professor
Secondary  OB/GYN   OB/GYN - Maternal & Fetal Medicine Professor
Center  Center for Metabolic Bone Disease  Center for Metabolic Bone Disease Professor

Biographical Sketch 
Dr. Faye-Petersen is an internationally recognized perinatal pathologist, author, and lecturer. She received her undergraduate (biology, chemistry, and philosophy) and medical degrees from the University of Colorado. She completed residency training at the Denver Presbyterian Hospital in Denver, CO, and later completed postdoctoral training in Surgical Pathology at the Memorial Sloan-Kettering Cancer Center and pediatric pathology at Mount Sinai Medical Center in New York City, NY. Since 1996, she has been cited in the annual publications of "Best Doctors in America." In February 2002, she was received the Society for Pediatric Pathology’s (SPP's) Distinguished Colleague Award. In March 2007, she was named the Outstanding Woman UAB Faculty Member for her academic, teaching, research, and community service contributions. In March 2011, Dr. Faye-Petersen was awarded the President's Scroll of Appreciation for her outstanding service to the SPP's educational efforts. Long committed to multidisciplinary education, Dr. Faye-Petersen has received numerous UAB School of Medicine teaching awards, and, in 2010, was one of two UAB School of Medicine faculty inducted into Alpha Omega Alpha National Honor Society. Finally, she was instrumental in starting, and continues to remain active in, the UAB Commission for the Status of Women's annual community clothing drive, "Suits for Success." This drive is the major contributor to the YWCA of North Central Alabama's resource, "My Sister's Closet," for interviewing and work attire, for economically disadvantaged women. This UAB drive results in the annual collection at least two tons of such clothing and accessories from UAB donors and the surrounding regional communities; February 2013 marked the 8th Annual UAB S4S drive.

Society Memberships
Organization Name Position Held Org Link
American Society of Human Genetics     
College of American Pathologists  Fellow   
International Federation of Placental Associations      
International Pediatric Pathology Association  Council Member 2006 - 2010   
International Placental Pathology Society      
Jefferson County Medical Society      
Society for Maternal-Fetal Medicine, Formerly Society for Perinatal Obstetricians     
Society for Pediatric Pathology  Education Committee Chair 2008-2011, Director for SPP sponsored Perinatal Pathology Course:;5/2005; 5/2008; Councilor-at-Large 2006-2008, 2011-2015   
United States and Canadian Academy of Pathology (IAP)      

Research/Clinical Interest
Title
Perinatal and Placental Pathology
Description
Dr. Faye-Petersen's service responsibilities and areas of research activities are largely focused on perinatal and placental pathology. Through the combined support of the Department of Pathology and UAB Hospital, in 1995, she established a diagnostic regional referral service laboratory for embryo-fetal and placental pathology, the UAB Microdissectional Laboratory (MDL). From 7/1995 through 1/2009, the MDL provided in-depth multidisciplinary evaluations of conceptus specimens delivered from women with histories of recurrent, spontaneous abortion; fetuses and placentas from pregnancies with antenatally documented or suspected abnormalities and genetic syndromes; cases of intrauterine fetal demise; and placentas from stillborn or live born infants whose gestations were complicated by maternal disease or other adverse factors. In 2/2009, the outreach autopsy aspect of the MDL was discontinued, due to financial constraints. However, in late 2009, the need for such evaluations was addressed through its addition the outreach services of the UAB Autopsy Service, where Dr Faye-Petersen continues to perform postmortem examinations of stillborns and cases of infant death. MDL placental evaluations have continued to provide UAB and community obstetricians with pathologic correlations for prenatal clinical and ultrasonographic diagnoses, and have helped to answer questions concerning the causes of pregnancy loss, fetal growth restriction and maldevelopment, and neonatal complications. The MDL examinations also provide information essential for meaningful medical genetics counseling, grief counseling for patients and their families, and clinicopathologic correlations useful to future care of obstetrical and infant patients. MDL and UAB Autopsy Pathology Service work has enabled Dr Faye-Petersen to participate in several NIH-funded clinical research studies and collaborative studies with other placental pathologists to elucidate which placental pathologic findings may correlate with increased risks for perinatal morbidity and mortality, or underlying maternal disorders . Dr. Faye-Petersen is the lead author of the Handbook of Placental Pathology, published in 2006. In addition to her role as UAB's perinatal pathologist, Dr. Faye-Petersen is also the primary autopsy pathologist for cases complicated by congenital cardiovascular malformations. In 1997, she and two colleagues completed a re-examination and registry of UAB's cases of congenital heart disease. As primary investigator of this aspect of the UAB Congenital Heart Disease Program (CHDP), she established a formal, centralized site for the ongoing collection of formalin-fixed specimens with congenital heart malformations (some 650 to date) to support multidisciplinary education and research in the pathology and pathogenesis of cardiovascular malformations.

Selected Publications 
Publication PUBMEDID
Taylor GP, Faye-Petersen OM, Ernst L, LeGallo RD, Schauer GM, Williamson AK, Pacheco MC. Small patients, complex challenging cases -A reappraisal of the professional efforts in perinatal autopsies. Arch Pathol Lab Med. 2014 Epub 2014 Feb 3 ahead of print.

Salas AA, Faye-Petersen O, Sims B, Peralta-Carcelen M, Reilly SD, Andrews AA, Carlo WA,
Ambalavanan N. Severe fetal inflammatory response is associated with neurodevelopmental impairment or death in extremely preterm infants. J Pediatr. 2013;163(3):652-657.

Subramaniam A, Cliver SP, Andrews WW, Faye-Petersen OM, Goldenberg RL, Biggio JR Jr. Effect of corticosteroid interval on markers of inflammation in spontaneous preterm birth. Am J Obstet Gynecol 2013 Oct;209:379.e1-6. doi: 10.1016/j.ajog.2013.05.048. Epub 2013 Jun 11.


 
 
Faye-Petersen O, Ernst L. Placental maternal floor infarction/ massive perivillous fibrinoid deposition. Invited review. Surg Pathol Clinics. 2013;6:127-151. Baergen RN, Issue Editor for Placental Pathology
 
 
Faye-Petersen O, Kapur R. Placental mesenchymal dysplasia. Invited review. Surg Pathol Clinics. 2013;6:101-114. Baergen RN, Issue Editor for Placental Pathology.
 
 
Chassaing N, Sorrentino S, Davis EE, Martin-Coignard D, Iacovelli A, Paznekas W, Webb BD, Faye-Petersen O, Encha-Razavi F, Lequeux L, Vigouroux A, Yesilyurt A, Boyadjiev SA, Kayserili H, Loget P, Carles D, Sergi C, Puvabanditsin S, Chen CP, Etchevers HC, Katsanis N, Mercer CL, Calvas P, Jabs EW. Mutations in the OTX2 gene are involved in otocephaly-dysgnathia.OTX2 Mutations contribute to the otocephaly-dysgnathia complex. J Med Genet. 2012;49:373-9.

Ho M, Faye-Petersen O, Goldenberg RL, Carlo WA, Cliver SP, Andrews WW. Elevated midtrimester alpha-fetoprotein is associated with increased perinatal death but a low rate of inflammation in a preterm population. J Matern Fetal-Neonat Med. 2012; 25:2424-7. 
 
Lo AA, Faye-Petersen O, Ernst LM. Intrauterine fetal death of a monchorionic twin with peripheral pulmonary infarcts: Potential thromboembolic events following death of co-twin. Pediatr Dev Pathol. 2012;15:142-5.
 
 
Faye-Petersen O. The Placenta in Preterm Birth. J Clin Pathol 2008;61:1261-1275; doi:10.1136.

 
 
Faye-Petersen OM, Crombleholme TM. Twin-to-Twin Transfusion Syndrome: Part 1: types and pathogenesis. NeoReviews. 2008;9:e370-e379.

Faye-Petersen OM, Crombleholme TM. Twin-to-Twin Transfusion Syndrome. Part 2: Infant anomalies, clinical interventions and placental examination in chronic TTTS. NeoReviews. 2008;9:e380-e392.

Faye-Petersen OM, Crombleholme TM. Twin-to-Twin Transfusion Syndrome. Part 3: Mortality and neurodevelopmental outcomes following clinical intervention in chronic TTTS. NeoReviews. 2008;9:e393-e398.


 
 
Faye-Petersen OM, Reilly SD. Demystifying the pathologic diagnoses of villitis and fetal thrombotic vasculopathy. NeoReviews. 2008;9:e399-e410.   
Reilly SD, Faye-Petersen OM. Chorioamnionitis and funisitis: their implications for the neonate. NeoReviews. 2008;9:e411-e417.   
Lakey M, Klein MJ, Faye-Petersen O. A comprehensive clinicopathologic analysis suggests that vascular endothelial growth factor (VEGF) is the most likely mediator of periosteal new bone formation (PNBF) associated with diverse etiologies. Clinical Medicine: Arthritis and Musculoskeletal Disorders. 2008;2:43-58.   
Andrews WW, Cliver S, Biasini F, Peralta-Carcelen M, Rector R, Arliksson-Schmidt A, Faye-Petersen O, Carlo W, Goldenberg R, Hauth JC. Early preterm birth: Association between in utero exposure to acute inflammation and severe neurodevelopmental disability at 6 years of age. Am J Obstetr Gynecol. 2008;198:466.e1-466.e11.   
Goldenberg RL, Andrews WW, Goepfert AR, Faye-Petersen O, Cliver SP, Hauth JC. The Alabama Preterm Birth Study: Umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominus cultures in very preterm newborns. Am J Obstet Gynecol. 2008;198:43.e1-43.e5.    
Goldenberg RL, Faye-Petersen O, Andrews WW, Goepfert A, Cliver SP,. Hauth JC. The Alabama Preterm Birth Study: Diffuse decidual leukocytoclastic necrosis of the decidua basalis, a placental lesion associated with preeclampsia, indicated preterm birth, and decreased fetal growth. J. Mat Fet Neonatal Med. 2007;20:391-395.   
Faye-Petersen O, David E, Rangwala N, Seaman JP, Hua Z, Heller DS. Otocephaly-Report of five new cases & literature review. Fetal Pediatr Pathol. 2006;25:277-296.   
Faye-Petersen O, Heller DS, Joshi VV. Handbook of Placental Pathology. Taylor and Francis Medical Publishers, Oxford England, 2006.    
Redline RW, Faye-Petersen O, Heller D, Quereshi F, Savell V, Vogler C. Amnionic Fluid Infection: Nosology and reproducibility of placental reaction patterns. Pediatr Develop Pathol. 2003;6:435-438.

Faye-Petersen O, Guinn BA, Wenstrom KD Value of perinatal autopsy Obstets Gynecol 1999;94(6):915-920
 
 

Keywords
perinatal pathology, congenital cardiovascular malformations