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Faculty Detail    
Name ISAM-ELDIN ELTOUM
 
Campus Address HSB 122 Zip 6823
Phone 205-934-4333
E-mail ieltoum@uab.edu
Other websites http://cyto.path.uab.edu
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pathology   Anatomic Pathology Professor

Graduate Biomedical Sciences Affiliations
Cancer Biology 
Genetics and Genomic Sciences 
Molecular and Cellular Pathology Program 
Pathobiology and Molecular Medicine 

Biographical Sketch 
Dr. Eltoum received his medical degree from the School of Medicine University of Khartoum, Sudan (1983), where he subsequently did a residency in Clinical Pathology and received a master degree in clinical pathology. Then he was appointed as an assistant professor at his alma mater. In 1993 he finished a postdoctoral fellowship at the NIH then he did a residency training in Anatomic Pathology at George Washington University, and a cytopathology and a surgical pathology fellowships at the Department of Pathology, University of Alabama at Birmingham, where he currently heads the Cytopathology Section at the Division of Anatomic Pathology, Department of Pathology and direct the Cytotechnology School, School of Allied Health Professions.

Society Memberships
Organization Name Position Held Org Link
Alabama Association of Pathologists   President   
College of American Pathologists  Fellow   
The Royal College of Pathologists  Member   
USCAP  Member   

Research/Clinical Interest
Title
- Clinical research in diagnostic cytology and surgical pathology- Tumorogenesis of prostate cancer and chemoprevetion - HPV infection
Description
Dr. Eltoum's clinical interest involves general diagnostic cytology and surgical pathology. In particular he is interested in cytologic, histologic features and biomarkers that are associated with tumor progression and patient's survival in prostate, cervical and pancreatic tumors. He is also interested in utilization of new techniques in diagnostic cytopathology particularly FISH analysis, HPV DNA testing and EUS-FNA.

Selected Publications 
Publication PUBMEDID
Eltoum IA, Roberson J. Impact of expected changes in national Papanicolaou test volume on the cytotechnology labor market: an impending crisis. Am J Clin Pathol. 2007;128 (4):665-70.   
Kulesza P, Eltoum IA. Endoscopic ultrasound-guided fine-needle aspiration: sampling, pitfalls, and quality management. Clin Gastroenterol Hepatol. 2007 Nov;5(11):1248-54.    
Eloubeidi MA, Morgan DE, Cerfolio RJ, Eltoum IA. Transduodenal EUS-guided FNA of the right adrenal gland. Gastrointest Endosc. 2008 Mar; 67(3):522-7.    
Liu Z, Eltoum IE, Guo B, Beck BH, Cloud GA, Lopez RD. Protective Immunosurveillance and Therapeutic Antitumor Activity of {gamma}{delta} T Cells Demonstrated in a Mouse Model of Prostate Cancer. J Immunol. 2008 May 1; 180(9):6044-53.   
Harper CE, Patel BB, Cook LM, Wang J, Shirai T, Eltoum IA, Lamartiniere CA. Characterization of SV-40 Tag rats as a model to study prostate cancer. BMC Cancer. 2009 Jan 26;9: 30.   
Roberson J, Eltoum IA. Cytotechnology labor market: an update. Am J Clin Pathol. 2010 Nov;134(5):820-5.   
Crowe A, Linder A, Hameed O, Salih C, Roberson J, Gidley J, Eltoum IA. The impact of implementation of the Bethesda System for Reporting Thyroid Cytopathology on the quality of reporting, "risk" of malignancy, surgical rate, and rate of frozen sections requested for thyroid lesions. Cancer Cytopathol. 2011 Oct 25;119(5):315-21.   
Knight CS, Eloubeidi MA, Crowe R, Jhala NC, Jhala DN, Chhieng DC, Eltoum IA. Utility of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and staging of colorectal carcinoma. Diagn Cytopathol. 2011 Sep 19.    
Eltoum IA, Alston EA, Roberson. Trends in pancreatic pathology practice before and after implementation of endoscopic ultrasound-guided fine-needle aspiration: an example of disruptive innovation effect? Arch Pathol Lab Med. 2012 Apr;136(4):447-53.   
Anderson PD, McKissic SA, Logan M, Roh M, Franco OE, Wang J, Doubinskaia I, Meer Rv, Hayward SW, Eischen CM, Eltoum IE, Abdulkadir SA. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. J Clin Invest. 2012 May 1;122(5):1907-19.    
Eloubeidi MA, Khan AS, Luz LP, Linder A, Moreira DM, Crowe DR, Eltoum IA. Combined use of EUS-guided FNA and immunocytochemical stains discloses metastatic and unusual diseases in the evaluation of mediastinal lymphadenopathy of unknown etiology. Ann Thorac Med. 2012 Apr;7(2):84-91    
Eltoum I, Chhieng DC, Roberson R, McMillon D, Partridge E. Reflex human papilloma virus infection testing detects the same proporation of cervical intraepithelial neoplasia grade 2-3 in young versus elderly women. Cancer Cytopathology. 25;105(4):194-8, 2005.   
Eltoum IA, Siegal GP, Frost AR. Microdissection of Histologic Sections: Past, Present and Future. Advances in Anatomic Pathology 9(3) 2002.   
Eltoum IA, Wynn TA, Poindextor R, Finkelman F, Lewis FA, Sher A, Cheever A. Suppressive effect of anti-Interleukin-4 differ for granulomas around Schistosoma mansoni eggs injected into mice compare to eggs laid by the worm in infected mice.    
Eltoum IA, Tabbara S. Intra-operative cytologic smear in the diagnosis of granuloma:    
Wang J. Eltoum IE. Lamartiniere CA. Dietary Genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats. Cancer Letters. 186(1):11-8, 2002    
Fritz WA. Eltoum IE. Cotroneo MS. Lamartiniere CA. Genistein alters growth but is not toxic to the rat prostate. Journal of Nutrition. 132(10):3007-11, 2002    
Eltoum I, Eloubeidi, M, Chhieng, D., Tamhane, A, Crowe, R, Jhala, M, St John, K, Wilcox, M.C, Siegal, GP, Vickers, S, Jhala, N Cytologic grade independently predicts survival of patients with pancreatic adenocarcinoma. American Journal of Clinical Pathology. 124(5):1-11, 2005   
Yang SZ, Eltoum IA, Abdulkadir SA. Enhanced EGR1 activity promotes the growth of prostate cancer cells in an androgen depleted environment. Journal of Cellular Biochemistry. 2006; 15; 97(6):1292-9.   

Keywords
EUS-FNA, Prostate cancer in transgenic animals, HPV infection, Cytology, Immunopathology