Back to Main

Faculty Detail Faculty Entry   
Name JOHN JOSEPH HABLITZ  
Campus Address SHEL 1014 Zip 2182
Phone 205-934-0742
E-mail jhablitz@uab.edu" id="FacultyDetail1EmailAddress"><a href="mailto:jhablitz@uab.edu">jhablitz@uab.edu</a>
URL
 
 

Department Affiliations(s)
Appointment Type Department Division Rank
Center  Civitan International Research Center  Civitan International Research Center Professor
Center  Ctr for Glial Bio in Med  Ctr for Glial Bio in Med Professor
Primary  Neurobiology  Neurobiology Professor
Secondary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Professor

Biographical Sketch 
John Hablitz received his Ph.D. in Psychology from the University of Houston in 1972. Following an Associate Professor position at Baylor College of Medicine, he joined UAB in 1989. He is presently Professor of Neurobiology.

Society Memberships
Organization Name Position Held Org Link
American Epilepsy Society  Member  www.aesnet.org 
Society for Neuroscience  Member  www.sfn.org 
 

Research/Clinical Interest
Title
Cellular Mechanisms of Neurotransmission
Description
Dr. Hablitz is using studies on synaptic transmission to further understand basic biophysical properties of mammalian central neurons, as well as to explore the pathophysiology of experimental epilepsy. Electrophysiological techniques, including whole-cell voltage-clamp recordings from visually identified neurons, are used in brain slice preparations. The goal of these studies is to determine the types of synaptic interactions present among pyramidal cells and interneurons in neocortex and how these patterns change during development. Additional studies involve the use of optical imaging techniques. These studies examine the role of presynaptic receptors in regulating glutamate and GABA release from individual synaptic boutons in normal neocortex and an animal model of cortical dysplasia.

Postdoc Positions Available
Date Posted Position Title
No records
 

Selected Publications 
Publication PUBMEDID
Calfa, G., Hablitz, J.J. and Pozzo-Miller, L. Network hyperexcitability in hippocampal slices from mecp2 mutant mice revealed by voltage-sensitive dye imaging. J Neurophysiol. 2011, 105:1768-84.   21307327 
Albertson, A., Yang, J. and Hablitz, J.J. Decreased hyperpolarization-activated current (Ih) in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia. J Neurophysiol. 2011 Jul 27.   21307327 
Mathew, S.S. and Hablitz, J.J. Presynaptic NMDA receptors mediate IPSC potentiation at GABAergic synapses in developing rat neocortex. PlosOne 2011, 6:e17311.   21365001 
Mathew, S.S., Pozzo-Miller, L. and Hablitz, J.J. Kainate modulates presynaptic GABA release from two vesicle pools. J. Neurosci. 2008, 28:725-731  18199771 
Campbell, S.L., Mathew, S.S., Hablitz, J.J. Pre- and postsynaptic effects of kainate on layer II/III pyramidal cells in rat neocortex. Neuropharmacology, 2007, 53: 37-47.  17543353  
Bandyopadhyay, S., Sutor, B. and Hablitz, J.J. Endogenous acetylcholine enhances synchronized interneuron activity in rat neocortex. J Neurophysiol, 2006; 95: 1908-1916  16338999 
Campbell, SL and Hablitz, JJ. Glutamate transporters regulate excitability in local networks in rat neocortex. Neuroscience. 2004;127(3):625-35.  15283962  
Keros, S and Hablitz, JJ. Subtype-specific GABA transporter antagonists synergistically modulate phasic and tonic GABAA conductances in rat neocortex. J Neurophysiol. 2005, 94:2073-85.  15987761 
Wu, JP and Hablitz, JJ.Cooperative activation of D1 and D2 dopamine receptors enhances a hyperpolarization-activated inward current in layer I interneurons.
J Neurosci. 2005, 25:6322-8 		 16000622  
Gonzalez-Islas C and Hablitz, JJ. Dopamine enhances EPSCs in layer II/III pyramidal neurons in rat prefrontal cortex. J. Neurosci. 2003, 23: 867-875.  12574415 
First Prev   1 2 of  2  Next Last  

Keywords

© 2003 University of Alabama School of Medicine. Copyright Information. UAB Disclaimer.
Contact the MEIS Help Desk if you experience problems with this site.