Biochemistry and Structural Biology  http://www.gbs.uab.edu  http://www.uab.edu/graduate  Back to Main
 Faculty Listing
Total Records: 96
Last Name First Name Research/Clinical Interest Title Keywords
AGARWAL ANUPAM Regulation of heme oxygenase gene expression in kidney and vascular injury heme oxygenase, acute renal failure, atherosclerosis, transcriptional gene regulation
ALLER STEPHEN Structure and Function of Human Membrane Proteins Research/Clinical Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer
ALMEIDA JONAS Computational Infrastructure for Integrative Bioinformatics Informatics, computational statistics
ANANTHARAMAIAH G Apolipoproteins, Amphipathic Helices and Atherosclerosis
BAILEY SHANNON Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Functional proteomics; Nitric oxide; Free radical biology; Toxicology
BARNES STEPHEN Bile acids, polyphenols and metabolism, and their effects on protein expression and function in chronic disease bile acids, isoflavonoids and polyphenols, metabolomics, proteomics, mass spectrometry
BASU MALAY Computational Genomics and Bioinformatics Genomics, bioinformatics, high-performance computing, grid computing, computational biology, evolution
BELLIS SUSAN Cell/matrix interactions in disease and tissue regeneration integrin, death receptors, cell adhesion, apoptosis, signal transduction, glycosylation, extracellular matrix, bone, biomaterials, tissue engineering
BJORNSTI MARY-ANN DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer
BLUME SCOTT Specific regulation of gene expression at the translational level - through sequence-specific RNA-binding proteins and complex 5'-untranslated RNA sequences; dysregulation of gene-specific translational control mechanisms in cancer. RNA-binding proteins, gene-specific translational regulation, breast cancer, c-myc, IGF1R, internal ribosomal entry site (IRES).
BRAUNEWELL KARL-HEINZ Molecular and Cellular Neurobiology, Function of neuronal calcium sensors in health and disease neuronal calcium sensor, glioblastoma, tumor invasion, signal transduction
BRENNER MICHAEL Molecular Sudies of Astrocytes in Health and Disease astrocyte, GFAP, transcription, neurodegeneration, transgenic mice
BROUILLETTE CHRISTIE Protein Structural Cooperativity and Energetics calorimetry, protein folding, thermodynamics, drug discovery
BUCHSBAUM DONALD Cancer immunotherapy Immunotherapy, apoptosis, pancreatic cancer, breast cancer, ovarian cancer
CAPRIOTTI EMIDIO Computational Biology/Bioinformatics protein and RNA three-dimensional structure, folding and stability, genomic variations, disease-related variants, machine-learning
CHATTOPADHYAY DEBASISH Structure-Function Analysis of Proteins Structural biology, Protein structure function, Malaria, Chagas' disease, Parasitic disease, Small pox, Bacterial pneumoniae
CHEN CHING-YI Mechanism and Regulation of Mammalian mRNA Turnover Post-transcriptional regulation, RNA-binding protein, Adipocyte function
CHESNOKOV IGOR DNA Replication and Cell Cycle in Eukaryotes DNA replication, cytokinesis, Origin Recognition Complex
CHOW LOUISE Human papillomavirus DNA replication and pathogenesis HPV infections and cancers
DEIVANAYAGAM CHAMPION
DELUCAS LAWRENCE Protein Crystallography/Structure-based Drug Design/Protein Crystal Growth structural biology, drug design, biotechnology
DOKLAND TERJE Structural biology of viral assembly and bacterial pathogenicity Staphylococcus, pathogenicity, virus, assembly, bacteriophages, electron microscopy, crystallography, 3D reconstruction
ELGAVISH GABRIEL NMR Studies of Intact Hearts
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
GILES KEITH Transcripiton, Chromatin, and Pluripotentcy Argonatue, RNAi, insulator, nucleosomes
GOLDMAN FREDERICK Creation of patient-specific gene corrected hematopoietic stem cells in inherited bone marrow failure syndromes using inducible pluripotent stem cell technology gene therapy, telomerase, hematopoiesis, inducible pluripotent stem cells, oxidative stress, DNA damage response pathways
GRAVES DAVID
GRAY MICHELLE Pathogenesis of Huntington's Disease Huntington's disease, neurodegeneration, neuroscience, astrocytes
GREEN TODD Viral Transcription and Replication, Capsid Structure
GROSS ALECIA GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, evi5, DENND4a, retinal degeneration, inflammatory response in retina
HABEGGER KIRK FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation
HALADE GANESH Cardiac Remodeling in the Setting of Obesity following Myocardial Infarction and Resolution of Inflammation Aging, Cardiac Remodeling, Cyclooxygenase, Extraceullar matrix, Fatty acids, Heart failure, Inflammation, Lipoxygenase, Myocardial infarction, Obesity
HARTMAN JOHN Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, aging, cystic fibrosis, dNTP metabolism, systems biology, drug discovery, lab automation
HASSAN MOHAMMAD MicroRNA and Epigenetic Regulation of Bone and Tooth Formation MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation
HIGGINS N
HIGGINS N Genetic and Biochemical Studies of Chromosome Dynamics Topoisomerases, Transposition, Site-specific Recombination, Genetics
HOLMES ROSS Oxalate Handling and Synthesis and its Relationship to Health and Disease urolithiasis, oxalate, glycolate, hydroxyproline, metabolism
HU KEJIN Molecular mechanisms of somatic cell reprogramming to pluripotency; self-renewal of pluripotent stem cells (PSC); Pluripotency; Epigenetics of PSC and reprogramming Reprogramming; embryonics stem cells; Induced pluripotent stem cells; pluripotency; epigenetics
HUNTER CHAD Transcriptional control of pancreatic beta cell development and adult islet cell function Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology
JIANG HAO Epigenetic regulation of animal cell fate histone methylation, transcription, stem cell
KEDISHVILI NATALIA Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid vitamin A, retinoic acid, oxidoreductases, development, differentiation
KHARLAMPIEVA EVGENIA stimuli-responsive polymers, drug delivery, cell surface engineering, protein assembly at interfaces
KLUG CHRISTOPHER Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer
KRISHNA N Structural Biology and Biomolecular NMR Spectroscopy Proteins, Structural Biology, NMR
LEFKOWITZ ELLIOT Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics
LI YONGHE
LIMDI NITA Pharmacogenetics of drug response Pharmacogenetics, Pharmacogenomics, Pharmacoepidemiology, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness
LOTHROP CLINT
LUCIUS AARON
MOBLEY JAMES Director, Urologic & Clinical Proteomics Research Facility, Associate Director, Shared Mass Spectrometry Facility Urology, Cancer, Prostate, Pancreatic, Breast, Cervical, Biomarkers, Mass Spectrometry, MALDI, Tissue Imaging, Hormones
MORGAN SARAH Nutrition, osteoporosis, bone densitometry, folic acid, methotrexate
MUCCIO DONALD Retinoids for cancer prevention and therapy
NAHM MOON Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines pneumococcus, capsule, innate immunity, pathogenesis, vaccines
NAPIERALA MAREK
NIEDERWEIS MICHAEL Novel proteins in the outer membrane of mycobacteria: Functions, structures, role in tuberculosis and applications tuberculosis, virulence, antibiotic resistance, membrane, proteins, transport, nanotechnology
NOAH DIANA
NOAH JAMES
NOVAK JAN Pathogenesis and treatments of chronic diseases, infectious diseases, cancer. IgA nephropathy. Mucosal immunology. Biomarkers.
PATEL RAKESH Modulation of Inflammation by Reactive Species and N-glycans vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan
PETIT CHAD
PITTLER STEVEN Basic and Translational Studies of Photoreceptor Metabolism and Retinal Degeneration retinitis pigmentosa, phosphodiesterase, cGMP-gated cation channel, photoreceptor, phototransduction
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
POPOV KIRILL Regulation of pyruvate dehydrogenase complex
PREVELIGE PETER Structural Biology of Viral Assembly and Infection
RAMANADHAM SASANKA Role of Lipid Mediators in Signal Transduction Islets, signal transduction, iPLA2, bone, protease inhibitors
RENFROW MATTHEW Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics
ROWE STEVEN Cystic Fibrosis Clinical and Translational Research cystic fibrosis, CFTR, nonsense mutations
RYAN THOMAS Stem Cell Therapies in Animal Models of Human Disease Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation
SAAD JAMIL HIV-Host Interactions and Fas-Mediated Apoptosis HIV, NMR, Cancer, Drug design
SCHNEIDER DAVID Control of RNA polymerase I transcription in the model eukaryote Saccharomyces cerevisiae cancer, gene expression, post-translational control, ribosomes
SEGREST JERE Structural Biology of Supramolecular Assemblies (Particularly Lipoproteins and Membranes)
SHA BINGDONG Structural and functional studies of proteins involved in protein folding and translocations
SMITH JEFFREY Integration of Prodeath and Prosurvival Signals by the Ubiquitin Proteasome System (UPS)
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
SONTHEIMER HARALD The Role of Neuroglia in Brain Function and Disease Cell migration, brain development, primary brain tumors, glioma, astrocytes, oligodendrocytes, stem cells, regeneration
SORSCHER ERIC Cystic Fibrosis and Molecular Genetics; Patient Oriented Research
STRONG THERESA Identification of Tumor Antigens and Development of Cancer Vaccines tumor antigen, immunotherapy, vaccine
SUDARSHAN SUNIL The Metabolic Basic of Kidney Cancer tumor metabolism, epigenetics, renal cancer
SZTUL ELIZABETH Membrane Traffic; Protein Degradation Cystic fibrosis, membrane traffic, degradation, quality control
THOMPSON SUNNIE Translation initiation and replication of RNA viruses Host pathogen interactions, Mechanisms of viral translation, IRES, Picornaviruses, Flaviviruses, Ribosome, Translational mechanisms in Cancer
TOWNES TIM Developmental Regulation of Gene Expression
TUCHOLSKI JANUSZ Cellular and molecular biology of neuroblastoma. Response of neuronal cells and neurons to stress. Tissue transglutaminase, cAMP, retinoic acid, neuronal death and survival, neuronal stress, plasticity, mice
TURNBOUGH CHARLES Structure/Function of the Bacillus anthracis Exosporium; Bacterial Gene Regulation anthrax, Bacillus anthracis, exosporium, E. coli, gene regulation. reiterative transcription, transcription start site switching
UNLAP M. Drug Discovery in Cancer, Cystic Fibrosis, Tuberculosis, Parkinson's Disease and Oxidative Stress In Hypertension drug discovery, oxidative stress, cancer, parkinson's disease, hypertension, exchanger, molecular beacon, latent tb
VAN WAARDENBURG ROBERT
VASSYLYEV DMITRY Structural studies of prokaryotic transcription
VELU SADANANDAN
WALTER MARK Structure, Biochemistry, and Function of Cytokines involved in Viral pathogenesis and Autoimmunity structural biology, immunology, virology, cytokine, signaling, vaccine, protein design, lupus, interferon, IL-10
WANG HENGBIN Role of Histone Modification in Chromatin and cellular Function epigenetics, histone modifications, ubiquitination and deubiquitination
WENDE ADAM Mechanisms of glucose mediated regulation of cardiac mitochondrial function Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4
WHITE C Oxidant Stress and Endothelial Dysfunction
WU HUI Microbiome, Bacteria and Host Interactions, Structural Biology and Glycobiology Microbiome, biofilms, protein glycosylation, osteoclastogenesis, and bone resorption
YANG QINGLIN Molecular and biochemical mechanisms of myocardial energy metabolism PPAR, ATP synthase, mitochondria, energy metabolism, fatty acid metabolism, glucose metabolism, heart failure, cardiac hypertrophy, diabetic cardiomyopathy
YOUNG MARTIN Role of the Circadian Clock within the Heart
YUSUF NABIHA Innate immune mechanisms in tumor development toll like receptors, immune system, cancer, T-cells
ZHAO XINYANG The roles of protein arginine methyltransferases in abnormal hematopoiesis Arginine methylation, epigenetics, leukemia, stem cell, transcription