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Faculty Detail    
Name SERGIO STAGNO
 
Campus Address ACC 600 Zip 0011
Phone 205-934-4280
E-mail sstagno@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pediatrics   Pediatrics Chair Office Professor
Center  Center for AIDS Research  Center for AIDS Research Professor
Center  Cystic Fibrosis Research Center  Cystic Fibrosis Research Center Professor

Biographical Sketch 
A native of Santiago, Chile, Dr. Stagno earned his undergraduate medical degrees at the University of Chile, followed by a residency in pediatrics at Roberto del Rio Children’s Hospital. He first came to UAB as a fellow in Perinatal Infectious Diseases in 1971. He rose through the ranks very quickly, becoming a Professor in 1980. In 1989, he was named Chairman of the Department of Pediatrics at UAB and Physician-in-Chief of the Children’s of Alabama. In recognition of his outstanding leadership and research, Dr. Stagno was appointed to the Katharine Reynolds Ireland Chair of Pediatrics in February 1993. Because of his tremendous administrative skills, he has also served as Interim Vice President for Health Affairs (1995) at UAB, Interim President of the University of Alabama Health Services Foundation (2008), and as President of the University of Alabama Health Services Foundation (2010-2012).

Research/Clinical Interest
Title
Description
Articles (selected from 142 publications) 1. Stagno S, Fowler KB, Pass RF, Britt WJ, Alford CA: The impact of primary and recurrent maternal cytomegalovirus (CMV) infection in the outcome of congenital infection. Excerpta Medica International Congress Series, Progress in Cytomegalovirus Research, 11-14, 1991 (Presented at the Third International Cytomegalovirus Workshop, Bologna, Italy, June 11-14, 1991). 2. Boppana SB, Pass RF, Britt WJ, Stagno S, Alford CA: Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality. Pediatr Infect Dis J 11:93-99, 1992. 3. Boppana SB, Smith RJ, Stagno S, Britt WJ: Evaluation of a microtiter plate fluorescent antibody assay for rapid detection of human cytomegalovirus infection. J Clin Microbiol 30:721-723, 1992. 4. Fowler KB, Stagno S, Pass RF, Britt WJ, Boll TJ, Alford CA: The outcome of congenital cytomegalovirus infection in relation to maternal antibody status. N Engl J Med 326:663-667, 1992. 5. Trang JM, Kidd L, Gruber W, Storch G, Demmler G, Jacobs R, Dankner W, Starr S, Pass R, Stagno S, Britt W, Alford C, Soong SJ, Whitley RJ, Sommadossi JP, NIAID Collaborative Antiviral Study Group: Linear single-dose pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. Clin Pharmacol Ther 53:15-21, 1993. 6. Fowler KB, Stagno S, Pass RF: Maternal age and congenital cytomegalovirus infection: screening of two diverse newborn populations, 1980-1990. J Infect Dis 168:552-556, 1993. 7. Stagno S, Cloud, GA: Working parents: The impact of day care and breast feeding on cytomegalovirus infection in offspring. Proceedings of the National Academy of Sciences, 9l:2384-2389, March l994. Colloquium Paper. 8. Boppana S, Amos C, Britt W, Stagno S, Alford C, Pass R: Late onset and reactivation of chorioretinitis in children with congenital cytomegalovirus infection. Pediatr Infec Dis J, 13:1139-42, 1994. 9. Boppana S, Fowler KB, Vaid Y, Hedlund G, Stagno S, Britt WJ, Pass RF: Neuroradiographic findings in the newborn period and long-term outcome in children with symptomatic congenital cytomegalovirus infection. Pediatr, 99:409-414, 1996. 10. Whitley R, Cloud G, Gruber W, Storch G, Demmler G, Jacobs R, Dankner W, Spector S, Starr S, Pass R, Stagno S, et al: Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a Phase II Study. J Infect Dis, 175:1080-1086, 1997. 11. Boppana S, Fowler KB, Britt WJ, Stagno S, Pass RF: Symptomatic congenital cytomegalovirus (CMV) infection in infants born to mothers with preexisting immunity to CMV. Pediatr, 104:55-60, 1999. 12. Rivera LB, Boppana S, Fowler KB, Britt WJ, Stagno S, Pass RF: Predictors of Hearing Loss in Children with Symptomatic Congenital Cytomegalovirus Infection. Pediatr, 110:762-767, 2002. 13. Stagno S: Breastfeeding and the Transmission of Cytomegalovirus Infections. Ital J Pediatr, 28:275-280, 2002. 14. Fowler KB, Stagno S, Pass RF: Maternal Immunity and Prevention of Congenital Cytomegalovirus Infection. JAMA, 289:1008-11, 2003. 15. Fowler KB, Stagno S, Pass RF: Interval Between Births and Risk of Congenital Cytomegalovirus Infection. CID, 38:1035-7, 2004. 16. Kanto WP, Stagno S: Medicaid…The Impending Storm. J Pediatr, 145:5, 2004. 17. Ross SA, Fowler KB, Ashrith G, Stagno S, et al: Hearing Loss in Children with Congenital Cytomegalovirus Infection Born to Mothers with Preexisting Immunity. J Pediatr, 332-36, 2006. Book Chapters (selected from 53 publications) 1. Stagno S, Cloud GA: Working parents: The impact of day care and breast feeding on cytomegalovirus infection in offspring. In: National Academy of Science Infectious Diseases in an Age of Change - The Impact of Human Ecology and Behavior on Disease Transmission. Roizman B. (ed) National Academy Press (Washington, D.C.) l995, pp l5-29. 2. Pass RF, Britt WJ, Stagno S: Cytomegalovirus. In: Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections,7th Edition, Lennette EH, Lennette DA, Lennette ET (eds), APHA, Chapter l5, pp 253-27l, l995 3. Stagno S: Cytomegalovirus, In: Oxford Textbook of Medicine, 3rd Edition, Weatherall D, Ledingham, JGG, Warrell, DA (eds), Oxford University Press, Oxford, England, l996, Section 7.l0.6, pp 359-363. 4. Whitley RJ, Stagno S: Perinatal Viral Infections. In: Infections of the Central Nervous System, 2nd Edition, Scheld WM, Whitley RJ, Durack DT (eds) Lippincott-Raven Publishing, (Philadelphia) l997, Chapter 16, pp 223-253. 5. Stagno S: Cytomegalovirus. In: Concise Oxford Textbook of Medicine, Ledingham JGG, Warrell DA (eds), Oxford University Press, New York, 2000, Section 16.14, pp 1509-1511. 6. Stagno S: Cytomegalovirus. In: Nelson Textbook of Pediatrics, 17th Edition, Behrman RE, Kliegman R, Jenson HB (eds), Saunders (Philadelphia), 2004, Section 11, Chapter 234, pp 1066-1069. 7. Stagno S, Britt W: Cytomegalovirus. In: Infectious Diseases of the Fetus and Newborn Infant, 6th Edition, Remington JS, Klein JO (eds), Elsevier Saunders (Philadelphia), 2006, Chapter 23, pp 739-781. C. Research Support Active 1K12HD43397 04/11/03 to 11/30/12 NICHHD National Inst. Of Child Health & Human Development Pediatric Physician Scientists in Translational Molecular Biology Principal Investigator Past P30HD96003 12/1/97 to 11/30/03 NICHHD National Inst. Of Child Health & Human Development Molecular Cell Biology in Pediatric Research Principal Investigator P30HD2883l 9/30/9l to 8/3l/96 NICHHD National Inst. Of Child Health & Human Development Molecular Cell Biology in Pediatric Research Principal Investigator P01HD10699 6/1/87 to 10/31/92 NICHHD National Inst. Of Child Health & Human Development Perinatal Infections, Immunity and Maldevelopment Dr. Charles Alford, Principal Investigator Dr. Sergio Stagno, Principal Investigator for Project 1, Maternal CMV Infection P01HD10699 6/1/82 to 6/30/87 NICHHD National Inst. Of Child Health & Human Development Perinatal Infections, Immunity and Maldevelopment Dr. Charles Alford, Principal Investigator Dr. Sergio Stagno, Principal Investigator for Project 1, Type of Maternal CMV Infection in Relation to Infection of the Offspring; Project 4, Development and Evaluation of Immunologic and Virologic Assays for the Detection of Congenital CMV Infection; Project 5, The Role of CMV Pneumonitis Syndromes in Infants Under Three Months of Age; and Project 8, Congenital Toxoplasmosis P01HD10699 6/1/77 to 5/31/82 NICHHD National Inst. Of Child Health & Human Development Perinatal Infections, Immunity and Maldevelopment Dr. Charles Alford, Principal Investigator Dr. Sergio Stagno, Principal Investigator for Project 1, Type of Maternal CMV Infection Relative to Intrauterine Transmission; Project 5, Evaluation of Virologic and Immunologic Assays for Congenital CMV Infection; Project 6, Pathogenetic Studies of Severe CMV Disease; and Project 9, Studies on Immune Complexes in Congenitally Acquired CMV THRASHER RESEARCH FUND l/l/83 to l2/3l/84 The Etiology of Infant Pneumonitis Principal Investigator Award No. 372 MARCH OF DIMES BIRTH DEFECTS 4/l/83 to 3/3l/87 FOUNDATION Factors Active in the In Utero Transmission and Virulence of Congenital Cytomegalovirus Principal Investigator Award No. March 6 l80 MARCH OF DIMES BIRTH DEFECTS 4/l/78 to 3/3l/82 FOUNDATION Congenital Toxoplasmosis: Evaluation of Diagnostic Methods, Long Principal Investigator

Keywords
cytomegalovirus (CMV)