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Faculty Detail    
Name EDWARD M POSTLETHWAIT
 
Campus Address RPHB 530 Zip 0022
Phone 205-934-7085
E-mail epost@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Center  Cystic Fibrosis Research Center  Cystic Fibrosis Research Center
Center  Medicine  Ctr Cardiovasc Bio

Graduate Biomedical Sciences Affiliations
Cell, Molecular, & Developmental Biology 
Immunology 
Integrative Biomedical Sciences 
Pathobiology and Molecular Medicine 

Research/Clinical Interest
Title
Environmental Induction of pulmonary epithelial injury
Description
Free radical biochemistry Pulmonary toxicology Quantitative morphology and image analysis Oxidant and antioxidant biochemistry Mechanisms of acute epithelial injury Effects of environmental oxidants on lung growth and development The pulmonary epithelial lining layer Dosimetry Physicochemical interactions of reactive gases with the lung surface

Selected Publications 
Publication PUBMEDID
Postlethwait E.M., Joad, J.P., Hyde, D.M., Schelegle, E.S., Bric, J.M., Weir, A.J., Putney, L.F., Wong, V.J., Velsor, L.W., and Plopper, C.G. Three-dimentional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung. Am. J. Respir. Cell Mol. Biol., 22 (2): 191-199, 2000.   
Postlethwait, E.M. and Ultman, J.S. Airspace surface chemistry mediates O3-induced lung injury. Int. J. Human Ecol. Risk Assess. 7:1145-1159, 2001.   
Jacobson, L.M., Bidani, A., Clements, J.A., Goerke, J. and Postlethwait, E.M. NO2 interfacial transfer is reduced by phospholipid monolayers J. Appl. Physiol. 91:2024-2034, 2001   
Connor, L.M., Ballinger, C.A., Albrecht, T.A., and Postlethwait, E.M. Interfacial phospholipids inhibit ozone reactive absorption-mediated cytotoxicity in vitro. Am. J. Respir. Cell Mol. Biol. In press.   
Velsor, L.W., Ballinger, C.A., Patel, J.M., and Postlethwait, E.M. Influence of epithelial lining layer lipids on NO2-induced membrane oxidation and nitration. Free Rad. Biol. Med. 34:720-733, 2003.