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Faculty Detail    
Name ROBERT F PASS
 
Campus Address CHB 309 Zip 0011
Phone 205-996-4104
E-mail rfpass@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pediatrics   Ped - Infectious Disease Professor
Secondary  Microbiology  Microbiology Professor
Center  Center for AIDS Research  Center for AIDS Research Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Professor
Center  General Clinical Research Center  Minority Health & Research Center Professor

Biographical Sketch 
B.S. Chemistry 1969, University of Alabama (Phi Beta Kappa)
M.D. University of Alabama School of Medicine, 1973 (Alpha Omega Alpha)
Pediatric Internship and Residency, Stanford University Medical Center, 1973-1976
Pediatric Infectious Diseases Fellowship, UAB Department of Pediatrics, 1976-1979
Faculty member, UAB Department of Pediatrics, 1979 to present
Director, Pediatric Hospital Medicine, March 1010 to present
Beth G. Dubina Endowed Chair in Pediatric Hospital Medicine, October 2011

Society Memberships
Organization Name Position Held Org Link
American Pediatric Society  member   
American Society for Microbiology  member   
American Society for Virology  member   
Infectious Diseases Society of America  Fellow   
Society for Pediatric Research  Member   

Research/Clinical Interest
Title
Prevention of maternal and congenital CMV infection
Description
My principal research interest is the development of vaccines for prevention of maternal and congenital cytomegalovirus (CMV) infection. Currently, two clinical trials, supported by both NIH and industry, are being conducted in healthy young women with an investigational CMV glycoprotein B vaccine. These clinical trials will test the ability of the vaccine to prevent CMV infection and will provide substantial new information on vaccine safety and immunogenicity. In addition, they will offer a remarkable opportunity to characterize the virologic and immunologic features of CMV infection in healthy young adults, information that will be of great importance for future CMV vaccine trials.

Selected Publications 
Publication PUBMEDID
Pass, RF: The Social ecology of infectious diseases transmission in day-care centers. In The Social Ecology of Infectious Diseases, K Mayer and H Pizer (eds), Elsevier, Burlington, MA, 2008.
 
n/a - book chapter 
Flynn, PM, Nachman, S, Muresan, P, Fenton, T, Spector, SA, Cunningham, CK, Pass, R, et al: Safety and immunogenicity of 2009 pandemic H1N1 influenza vaccination in perinatally HIV-1-infected children, adolescents, and young adults. J Infect Dis 206:421-30, 2012.  22615311 
Johnson, J, Anderson, B, Pass, RF: Prevention of maternal and congenital cytomegalovirus infection. Clin Ob Gyn 55:521-30, 2012.  22510635 
Cannon, MJ, Westbrook, K, Levis, D, Schleiss, MR, Thackeray, R, Pass, RF: Awareness of and behaviors related to child-to-mother transmission of cytomegalovirus. Preventive Medicine 54:351-7, 2012.  22465669 
Arav-Boger, R, Wojcik, GL, Duggal, P, Ingersoll, RG, Beaty, T, Pass, RF, Yolken, RH: Polymorphisms in toll-like receptor genes influence antibody responses to cytomegalovirus glycoprotein B vaccine. BMC Research Notes 5:140, 2012.  22414065 
Sabbaj, S, Pass, RF, Pichon, S, Goepfert, PA: CMV glycoprotein B vaccine is capable of boosting both antibody and CD4 T cell responses to CMV in chronically infected women. J Infect Dis 203:1534-41, 2011.   21592981 
Pass, RF: Dried blood spots and universal newborn screening for congenital cytomegalovirus infection. Clin Infect Dis, 52:582-584, 2011  21292662 
Murthy, S, Hayward, GS, Wheelan, S, Forman, MS, Pass, RF, Arav-Boger, R: Detection of a single identical cytomegalovirus (CMV) strain in recently seroconverted young women. PLoS One 6:e15949, 2011.  21264339 
Pass, RF: Congenital cytomegalovirus infection: screening and treatment. J Pediatr, 157:179-80, 2010.   20542286 
Hackett, DJ, Zhang, C, Stefanescu, C, Pass, RF: An ELISA for cytomegalovirus glycoprotein B antibody measurement in serum. Clin Vaccine Immunol 17:836-839, 2010.  20119875 
Pass, RF, Zhang, C, Evans, A, Simpson, T, Andrews, W, Huang, M, Corey, L, Hill, J, Davis, E, Flanigan, C, Cloud, G: Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med 360:1191-1199, 2009.  19297572 

Keywords
cytomegalovirus, congenital infection, vaccine development, pediatric HIV infection, clinical trials