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Faculty Detail    
Name MARCAS M BAMMAN
 
Campus Address MCLM 966A Zip 0005
Phone 205-996-7937
E-mail mbamman@uab.edu
Other websites www.uab.edu/exercise
     

Education
Undergraduate  Kansas State University    1989  BS - Exercise Science 
Graduate  UAB    1990  MA - Exercise Physiology 
Graduate  University of Florida    1996  PhD - Physiology 

Certifications
Certified Strength and Conditioning Specialist  1994 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Professor
Secondary  Medicine  Med-Gerontology/Geriatrics/Palliative Care Associate Professor
Secondary  Nutrition Sciences   Nutr Sci - Phys & Metabolism (Org Ret) Associate Professor
Center  Arthritis & Musculoskeletal Diseases Center  Arthritis & Musculoskeletal Diseases Center Professor
Center  Center for Biophysical Sciences/Engineering  Center for Biophysical Sciences/Engineering Professor
Center  Center for Metabolic Bone Disease  Center for Metabolic Bone Disease Professor
Center  Comprehensive Ctr for Healthy Aging  Comprehensive Ctr for Healthy Aging Professor
Center  Medicine  Comprehensive Diabetes Ctr (Org Ret) Professor
Center  General Clinical Research Center  Comprehensive Neuroscience Center Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Professor
Center  Cell, Developmntl, & Integrative Biology  Ctr for Exercise Medicine Professor
Center  Nutrition Sciences   Clin Nutrition Res (Org Ret) Professor
Center  Nutrition Sciences   Nutrition Obesity Res Ctr (NORC) Professor

Graduate Biomedical Sciences Affiliations
Cell, Molecular, & Developmental Biology 
Medical Scientist Training Program 
Pathobiology and Molecular Medicine 

Biographical Sketch 
Dr. Bamman was born in Manhattan, Kansas in 1966 and raised in St. Louis, Missouri. After earning a bachelor of science in exercise science from Kansas State University (1989) and a masters degree in exercise physiology from The University of Alabama at Birmingham (1990), he earned a PhD in the Department of Physiology at the University of Florida College of Medicine (1996). As a PhD candidate, Dr. Bamman traveled to the NASA Johnson Space Center in Houston, Texas where he conducted space flight-related research on skeletal muscle (studying load-mediated physiologic alterations) for nearly three years. He joined the UAB faculty in 1996. Dr. Bamman's research program focuses on skeletal muscle and exercise biology. He is the Director of the UAB Center for Exercise Medicine, and his interdisciplinary, translational research program involves co-investigators from Neurology, Geriatric Medicine, Cardiology, Surgery, Physical Therapy, and Rheumatology.

Additional appointments at UAB: Dr. Bamman holds secondary appointments in the Department of Nutrition Sciences and Department of Medicine (Division of Gerontology, Geriatrics, and Palliative Care). In addition to directing the UAB Center for Exercise Medicine, he holds appointments in the Comprehensive Cardiovascular Center, Comprehensive Neuroscience Center, Comprehensive Center for Healthy Aging, Comprehensive Arthritis, Musculoskeletal, Bone, and Autoimmunity Center, Nutrition Obesity Research Center, Comprehensive Diabetes Center, Center for Clinical and Translational Science, and Center for Biophysical Sciences and Engineering.

Society Memberships
Organization Name Position Held Org Link
American College of Sports Medicine  Fellow  www.acsm.org 
American Physiological Society  Professional Member  www.the-aps.org 

Research/Clinical Interest
Title
Skeletal muscle mass regulation in aging, disease, and exercise medicine
Description
Muscle atrophy and reduced functional capacity are well-established, deleterious consequences of acute (e.g., burn, trauma, disuse) and chronic (e.g., OA/HIV/RA/cancer cachexia, COPD, diabetes mellitus, spinal cord injury) conditions—the most widespread and insidious of which is the degenerative process of normal aging. Because the metabolic and contractile properties of skeletal muscle play essential roles in the overall health and function of the organism, gaining a better understanding of the mechanisms underlying muscle mass and phenotype regulation, as well as key processes to exploit in countermeasure development, is of utmost importance. To this end, mechanisms of adult human skeletal myogenesis and muscle mass regulation remain the overarching areas of study in our laboratory, with a prominent emphasis on the aging muscle. Our primary research objectives span three, inter-related focus areas in human subjects: Objective 1) to determine the cellular and molecular mechanisms driving muscle regeneration following damage or injury, while identifying differences responsible for regeneration impairment in the aging muscle; Objective 2) to better understand the primary etiology of muscle atrophy in acute (burn, trauma) and chronic (sarcopenia, cachexia) conditions; and Objective 3) to determine key processes responsible for myofiber hypertrophy in response to mechanical overload, and to exploit these processes with countermeasures to promote muscle re-growth in atrophied patients. To meet these objectives, we are using genomic, proteomic, and in vitro approaches to study the molecular regulation of muscle protein synthesis, proteolysis, and stem (satellite) cell function in humans experiencing atrophy and resistance training-induced hypertrophy. This translational research program takes full advantage of cellular and molecular studies in our Core Muscle Research Laboratory and in vivo functional assessments during clinical trials in the UAB Center for Exercise Medicine.

Selected Publications 
Publication PUBMEDID
Search "Bamman M" on PubMed via www.ncbi.nlm.nih.gov/pubmed   

Keywords
muscle atrophy, muscle function, protein synthesis, exercise medicine, satellite cell