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Faculty Detail     Name RICHARD C. SHELTON Charles B. Ireland Professor & Vice Chair for Research   Campus Address SC 1026 Zip 0017 Phone 205-975-9295 E-mail rshelton@uab.edu Other websites http://www.uab.edu/medicine/psychiatry/research/mood-disorders-research

Education Medical School  University of Louisville School of Medicine, Louisville, Kentucky    1979  M.D.

Faculty Appointment(s) Appointment Type Department Division Rank Primary  Psychiatry   Psych - Behavioral Neurobiology Professor Center  Center for Aging  Center for Aging Professor Center  General Clinical Research Center  Comprehensive Neuroscience Center Professor

Biographical Sketch  Dr. Shelton attended medical school at the University of Louisville in Kentucky. He, then, travelled to Boston, MA, where he became a resident and, then, Chief Resident at the Massachusetts Mental Health Center (now the Longwood Program), a teaching hospital of the Harvard Medical School. After residency, he was a research fellow at the National Institutes of Mental Health Intramural Program in Washington, D.C. before entering the faculty at Vanderbilt University in 1985. There he rose through the ranks to become the James G. Blakemore Research Professor and Vice Chair for Clinical Research in the Department of Psychiatry. He also became a professor in the Departments of Psychology and Pharmacology. Dr. Shelton joined the faculty of the Department of Psychiatry and Behavioral Neurobiology at the University of Alabama at Birmingham in February, 2012 as the Charles Byron Ireland Professor, Vice Chair for Research, and head of a newly formed Mood Disorders Research Center.

Society Memberships Organization Name Position Held Org Link American College of Neuropsychopharmacology  Member  http://www.acnp.org/  American Medical Association  Member  http://www.ama-assn.org/  American Psychiatric Association  Member  http://www.psych.org/  Society of Biological Psychiatry  Member  http://www.sobp.org

Research/Clinical Interest Title Mood Disorders Description Clinical Interests: Depression and Bipolar Disorder Dr. Shelton’s clinical specialization is adult patients with mood disorders, including depression and bipolar disorder. Research Interests: Mood Disorders Dr. Shelton’s research is on the causes and treatments of depression and bipolar disorder. He has a wide range of research activities, ranging from basic laboratory science to research translating from the lab to the clinic, to clinical investigations of new treatments for these common and serious conditions.

Selected Publications  Publication PUBMEDID Papakostas G.I., Shelton R.C., Zajecka J.M., Etemad B., Rickels K., Clain A., Baer L., Dalton E.D., Schoenfeld D., Pencina M., Meisner A., Bottiglieri T., Nelson E., Mischoulon D., Alpert J.E., Barbee J.G., Lydiard B., Zisook S., Fava M. l-methylfolate as adjunctive therapy for selective serotonin reuptake inhibitor-resistant major depressive disorder: results of two randomized, double-blind, parallel-sequential trials. American Journal of Psychiatry 169:1267-1274, 2012.  23212058   Shelton R.C. Does concomitant use of NSAIDs reduce the effectiveness of antidepressants? (Editorial). Am J Psychiatry 169:1012-1015, 2012.  23032377  Gibson SA, Korade Z, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. Journal of Psychiatric Research 46:1326-1332, 2012.  22841833  Treadway M.T., Buckholtz J.W., Cowan R.L., Woodward N.D., Li R., Ansari M.S., Baldwin R.M., Schwartzman A.N., Smith C.E., Bossaller N.A., Shelton R.C., Kessler R.M., Zald D.H. Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia. Journal of Abnormal Psychology 121:553-558, 2012.  22775583   Hayes R.M., Wu P., Shelton R.C., Cooper W.O., Dupont W.D., Mitchel E., Hartert T.V. Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies. American Journal of Obstetrics and Gynecology 207:49.e1-9, 2012.  22727349  Webb C., DeRubeis R., Dimidjian S., Hollon S., Amsterdam J., Shelton R. Predictors of patient cognitive therapy skills and symptom change in two randomized clinical trials: The role of therapist adherence and the therapeutic alliance. J Consult Clin Psychol 80:373-381, 2012.  22468907  Shelton R.C., Trivedi M.H. Using algorithms and computerized decision support systems to treat major depression. J Clin Psychiatry 72:e36, 2011.  22244032  Bobo W.V., Lynch A., Epstein R.A., Shelton R.C. A randomized, open comparison of long-acting injectable risperidone and treatment as usual for prevention of relapse, rehospitalization and urgent care referral in community-treated patients with rapid cycling bipolar disorder. Clin Neuropharmacol 34:224-233, 2011.  22104634  Carney R.M., Shelton R.C. Agomelatine for the treatment of major depressive disorder. Expert Opinion Pharmacother 12:2411-2419 2011.  21916789  Shelton R.C., Miller A.H. Inflammation in depression: is adiposity a cause? Dialogues Clin Neurosci 13:41-53, 2011.  21485745

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