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Faculty Detail     Name HELEN KIM   Campus Address MCLM 460 Zip 0005 Phone 205-934-3880 E-mail helenkim@uab.edu Other websites http://www.uab.edu/proteomics

Faculty Appointment(s) Appointment Type Department Division Rank Primary  Pharmacology/Toxicology   Pharmacology/Toxicology Chair's Office Associate Professor Secondary  Biochemistry & Molecular Genetics  Biochemistry & Molecular Genetics Associate Professor Research Secondary  Neurobiology  Neurobiology Assistant Professor Center  Neurology   Alzheimer's Disease Center Associate Professor Center  Arthritis & Musculoskeletal Diseases Center  Arthritis & Musculoskeletal Diseases Center Associate Professor Center  Center for Aging  Center for Aging Associate Professor Center  Comprehensive Cancer Center  Comprehensive Cancer Center Associate Professor Center  General Clinical Research Center  Comprehensive Neuroscience Center Associate Professor

Graduate Biomedical Sciences Affiliations Biochemistry and Molecular Genetics Program  Biochemistry and Structural Biology  Integrative Biomedical Sciences  Medical Scientist Training Program  Neuroscience  Pathobiology and Molecular Medicine

Biographical Sketch  Dr. Kim completed undergraduate studies at Mary Washington College of the University of Virginia (now Univ. Mary Washington) culminating in a BS in Chemistry. She completed a Master of Forest Science at Yale School of Forestry, and a PhD in Biophysics at the University of Virginia. Initially hired into the Dept of Cell Biology at UAB, she took a 2 yr hiatus at Molecular Geriatrics Corporation at Lake Bluff, IL, as Target Group leader under President and CEO Dr. Ferid Murad (Nobel Laureate, 1998, Medicine). Dr. Kim has been with the Dept of Pharmacology and Toxicology since 1995, and has directed the Proteomics component of the UAB Comprehensive Cancer Center Mass Spectrometry/Proteomics Shared Facility since its inception in 2000.

Society Memberships Organization Name Position Held Org Link Amer. Soc. Mass Spectrometry; Amer. Coll. Nutrition; Assoc. Advancement of Cancer Research; Polyphenols in human health research interest group (PHENHRIG)

Research/Clinical Interest Title Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals Description Dietary prevention of neurodegenerative conditions such as in Alzheimer's or following menopause; Brain microtubule assembly and function; The role of neurogenesis in learning and memory, as affected by dietary antioxidants; Molecular basis of health benefits of dietary polyphenols, anti-oxidants, and estrogen mimics.

Selected Publications  Publication PUBMEDID Barnes S, Kim H. Nutriproteomics: identifying the molecular targets of nutritive and non-nutritive components of the diet. J Biochem Mol Biol. 2004 Jan 31;37(1):59-74. Review.     Kim H, Hall P, Smith M, Kirk M, Prasain JK, Barnes S, Grubbs C. Chemoprevention by grape seed extract and genistein in carcinogen-induced mammary cancer in rats is diet dependent. J Nutr. 2004 Dec;134(12 Suppl):3445S-3452S.     Kim H. New nutrition, proteomics, and how both can enhance studies in cancer prevention and therapy. J Nutr. 2005 Nov;135(11):2715-8.     Kim H, Deshane J, Barnes S, Meleth S. Proteomics analysis of the actions of grape seed extract in rat brain: technological and biological implications for the study of the actions of psychoactive compounds. Life Sci. 2006 Mar 27;78(18):2060-5. Epub 2006 Jan 18

Keywords neuroprotection, proteomics, protein oxidations, chemoprevention, estrogen, neurogenesis

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