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Faculty Detail    
Name HELEN KIM
 
Campus Address MCLM 460 Zip 0005
Phone 205-934-3880
E-mail helenkim@uab.edu
Other websites http://www.uab.edu/proteomics
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pharmacology/Toxicology   Pharmacology/Toxicology Chair's Office Associate Professor
Secondary  Biochemistry & Molecular Genetics  Biochemistry & Molecular Genetics Associate Professor Research
Secondary  Neurobiology  Neurobiology Assistant Professor
Center  Neurology   Alzheimer's Disease Center Associate Professor
Center  Arthritis & Musculoskeletal Diseases Center  Arthritis & Musculoskeletal Diseases Center Associate Professor
Center  Center for Aging  COMPREHENSIVE CTR FOR HEALTHY AGING Associate Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Associate Professor
Center  General Clinical Research Center  Comprehensive Neuroscience Center Associate Professor

Graduate Biomedical Sciences Affiliations
Biochemistry and Molecular Genetics Program 
Biochemistry and Structural Biology 
Integrative Biomedical Sciences 
Medical Scientist Training Program 
Neuroscience 
Pathobiology and Molecular Medicine 

Biographical Sketch 
Dr. Kim completed undergraduate studies at Mary Washington College of the University of Virginia (now Univ. Mary Washington) culminating in a BS in Chemistry. She completed a Master of Forest Science at Yale School of Forestry, and a PhD in Biophysics at the University of Virginia. Initially hired into the Dept of Cell Biology at UAB, she took a 2 yr hiatus at Molecular Geriatrics Corporation at Lake Bluff, IL, as Target Group leader under President and CEO Dr. Ferid Murad (Nobel Laureate, 1998, Medicine). Dr. Kim has been with the Dept of Pharmacology and Toxicology since 1995, and has directed the Proteomics component of the UAB Comprehensive Cancer Center Mass Spectrometry/Proteomics Shared Facility since its inception in 2000.

Society Memberships
Organization Name Position Held Org Link
Amer. Soc. Mass Spectrometry; Amer. Coll. Nutrition; Assoc. Advancement of Cancer Research; Polyphenols in human health research interest group (PHENHRIG)     

Research/Clinical Interest
Title
Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals
Description
Dietary prevention of neurodegenerative conditions such as in Alzheimer's or following menopause; Brain microtubule assembly and function; The role of neurogenesis in learning and memory, as affected by dietary antioxidants; Molecular basis of health benefits of dietary polyphenols, anti-oxidants, and estrogen mimics.

Selected Publications 
Publication PUBMEDID
Barnes S, Kim H. Nutriproteomics: identifying the molecular targets of nutritive and non-nutritive components of the diet. J Biochem Mol Biol. 2004 Jan 31;37(1):59-74. Review.    
Kim H, Hall P, Smith M, Kirk M, Prasain JK, Barnes S, Grubbs C. Chemoprevention by grape seed extract and genistein in carcinogen-induced mammary cancer in rats is diet dependent. J Nutr. 2004 Dec;134(12 Suppl):3445S-3452S.    
Kim H. New nutrition, proteomics, and how both can enhance studies in cancer prevention and therapy. J Nutr. 2005 Nov;135(11):2715-8.    
Kim H, Deshane J, Barnes S, Meleth S. Proteomics analysis of the actions of grape seed extract in rat brain: technological and biological implications for the study of the actions of psychoactive compounds. Life Sci. 2006 Mar 27;78(18):2060-5. Epub 2006 Jan 18    

Keywords
neuroprotection, proteomics, protein oxidations, chemoprevention, estrogen, neurogenesis