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Faculty Detail    
Name CLYDE GUIDRY
  
Campus Address VH 490B Zip 0009
Phone 205-996-8673
E-mail cguidry@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Ophthalmology  Ophthalmology Associate Professor
Secondary  Cell Biology   Cell Biology Assistant Professor
Center  Medicine  Comprehensive Diabetes Ctr Associate Professor

Biographical Sketch 
Dr. Guidry completed his undergraduate studies at the University of Texas Arlington (1981) and graduate studies in Cell Biology at the University of Texas Health Science Center Dallas (1986). After postdoctoral studies in Biochemistry at the University of Alabama at Birmingham, Dr. Guidry joined the Department of Ophthalmology (1992).

Research/Clinical Interest
Title
Description
Dr. Guidry's studies are directed toward understanding the cell biology of acute (retinal tears and detachment) and chronic (diabetic retinopathy) fibroplastic changes in the retina. We are currently focused on understanding the process through which cells associated with retinal scar, develop tractional forces the cause of retinal detachment and perturbations. To this end, we use tissue culture models designed to mimic the intraocular environment, isolated populations of ocular cells established in culture and animal models. ( Dr. Guidry is currently principal investigator on NIH/NEI grant R01 EY 13258 and research grants from the Juvenile Diabetes Resesarch Foundation, International and the International Retinal Research Foundation.)

Selected Publications 
Publication PUBMEDID
Malek G, Guidry C, Bailey TM, Curcio CA. Age-related apolipoprotein and lipid accumulation in Bruch's membrane of normal human eyes. American Journal of Pathology. 2003;162(2):413-425.   
Guidry C, Bradley KM, King JL. Tractional force generation by human Müller cells: Growth factor responsiveness and integrin receptor involvement. Investigative Ophthalmology & Visual Science. 2003;44(3):1355-1363.   
Guidry C, Medeiros NE, Curcio CA. Phenotypic variation of retinal pigment epithelium in age-related macular degeneration. Investigative Ophthalmology & Visual Science. 2002;43(1):267-273.   
Mamballikalathil I, Mann C, and Guidry C. Tractional force generation by porcine Müller cells: Stimulation by RPE-secreted growth factors. Investigative Ophthalmology & Visual Science 2000;41(2):529-536.    
Guidry C. Tractional force generation by porcine Müller cells: Development and differential stimulation by growth factors. Investigative Ophthalmology & Visual Science 1997;38(2):456-467.    
Guidry C. Isolation and characterization of porcine Müller cells: Myofibroblastic differentiation in culture. Investigative Ophthalmology & Visual Science 1996;37:740-752.    
 

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