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Faculty Detail    
Name CRAIG M WILSON
 
Campus Address RPHB 523C Zip 0022
Phone 205-975-7608
E-mail cwilson@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Secondary  Medicine  Med - Geographic Medicine Professor
Secondary  Microbiology  Microbiology Professor
Secondary  Pediatrics   Pediatrics Chair Office Professor
Center  Center for AIDS Research  Center for AIDS Research

Biographical Sketch 
University of Wisconsin, Madison B.S. 1974
Peace Coprs Volunteer, Filariasis Control Program, (Western) Samoa 1974-78
University of Wisconsin School of Medicine M.D. 1982
Pediatric and Chief Residency, Stanford University Hospital, 1982-86
Pediatric Infectious Diseases Fellowship, Boston Children's Hospital, Harvard University, 1986-88
Research Fellow/Assistant, Dept of Tropical Diseases, Harvard School of Public Health, 1987-1991
Instructor, Department of Medicine, Harvard Medical School, 1989-91
Assistant Professor of Pediatrics,Medicine, Microbiology UAB, 1991-1999
Associate Professor of Pediatrics, Medicine, Microbiology and Epidemiology UAB, 1999 -2003
Professor of Pediatrics, Medicine, Microbiology and Epidemiology UAB, 2003-
Associate Scientist and member of Executive Committee (2002-); Director, International Core (2003-), Center for AIDS Research, UAB, 1991-

Research/Clinical Interest
Title
Description
My research efforts for the past 10 years have been almost exclusively related to HIV infections in adolescents, particularly those infected through risk behaviors. This work was initiated with the REACH study (1994-2001) and is continuing with the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) which started in 2001. The ATN is the only federally-funded HIV network focused on the domestic HIV epidemic in adolescents and young adults (ages 12-25), including those infected at birth as well behaviorally infected youth. The ATN has a broadly defined research agenda including primary prevention, management strategies and secondary prevention in these populations. The ATN has developed a community based primary prevention infrastructure in 14 cities which is now testing a community mobilization model as a prevention strategy with plans to test HIV vaccines and microbicides in adolescents in these communities. Planned and ongoing clinical based studies include therapeutic management strategies, interventions to enhance adherence and secondary risk reduction, and interventions to improve linkage and engagement in care. My other research interests are in the area of sustainable interventions for HIV prevention and control in resource poor areas. I, among other UAB faculty and Zambian collaborators, are working to support and facilitate the extensive ongoing HIV research and management work through the UAB affiliated Center for Infectious Disease Research in Zambia (CIDRZ).

Selected Publications 
Publication PUBMEDID
Murphy DA, Belzer M, Durako SJ, Saar M, Wilson CM, Muenz LR, for the Adolescent Medicine HIV/AIDS Research Network. Longitudinal Antiretroviral Adherence Among Adolescents Infected With Human Immunodeficiency Virus. Arch Pediatr Adolesc Med; 159: 764-770, 2005.   
Stephensen CB, Marquis GS, Douglas SD, Wilson CM. Immune Activation and Oxidative Damage in HIV-Positive and HIV-Negative Adolescents. J Acq Immune Defic Synd; 38(2):180-190, 2005.   
Bansal A, Gough E, Sabbaj S, Ritter D, Yusim K, Sfakianos G, Aldrovandi G, Kaslow RA, Wilson CM, Mulligan MJ, Kilby JM, and Goepfert PA. CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides. AIDS 19: 241-250, 2005.   
Wilson CM, Ellenberg JH, Douglas SJ, Moscicki A-B, and Holland CA for the REACH Project Of The Adolescent Medicine HIV/AIDS Research Network. CD8+CD38+ T Cells But Not HIV Type 1 RNA Viral Load Predict CD4+ T Cell Loss in a Predominantly Minority Female HIV+ Adolescent Population. AIDS Research and Human Retroviruses 20 (3): 263-269, 2004.   
Wilson CM, Gray G, Read JS, Mwatha A, Kaka S, Johnson S, Violari A, Sibiya PM, Fleming T, Koonce A, Vermund SH, and McIntyre J. Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025. JAIDS 35: 138-143, 2004.   
Tang J, Wilson CM, Meleth S, Myracle A, Lobashevsky E, Mulligan MJ, Douglas SD, Korber B, Vermund SH, Kaslow RA and the REACH Study Group. Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents. AIDS 16: 2275-2284, 2002.   
Wilson CM, Houser J, Partlow C, Rudy BJ, Futterman DC, Friedman LB, and The Adolescent Medicine HIV/AIDS Research Network. The REACH (Reaching for Excellence in Adolescent Care and Health) Project: Study Design, Methods, and Population Profile. J Adolesc Health 29 (3S): 8-18, 2001.   
Chiang C, Sullivan WS, Donald RGK, Roos DS, Carter N, Ullman B, Naguib FNM, el Kouni M, Wilson CM. The Adenosine Transporter of Toxoplasma gondii: Identification by Insertional Mutagenesis, Cloning, and Recombinant Expression. J Biol Chem 274: 35255-35261, 1999.   
Basco L, Rhoades MZ, Lebras J, and Wilson CM. Analysis of pfmdr1 and drug susceptibility in fresh isolates of P. falciparum from Subsaharan Africa. Mol Biochem Parasitol, 74:157-166, 1995.   
Wilson CM, Volkman SK, Thaithong S, Martin RK, Kyle DE, Milhous WK, Wirth DF. Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol Biochem Parasitol 57:151-160, 1993.   
Wilson CM, AE Serrano, A Wasley, M Bogenschutz, AH Shankar, DF Wirth. Amplification of a gene related to mammalian mdr genes in drug resistant Plasmodium falciparum. Science 244:1184-1186, 1989.   

Keywords
HIV, adolescents, malaria, tropical diseases, pararites