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Faculty Detail    
Name KEJIN HU
Assistant professor
PhD
 
Campus Address SHEL 705 Zip 2182
Phone 205-934-4700
E-mail kejinhu@uab.edu
Other websites
     

Education
Graduate  The Hong Kong Polytechnic University    1997  MPhil 
Graduate  University of Hong Kong    2003  PhD 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Biochemistry & Molecular Genetics  Biochemistry & Molecular Genetics Assistant Professor

Graduate Biomedical Sciences Affiliations
Biochemistry and Structural Biology 

Biographical Sketch 
Assistant professor in Stem Cell Biology since 2011; PhD in molecular biology from University of Hong Kong; MPhil in Biochemistry in microbiology from Hong Kong Polytechnic University; Postdoctoral training in muscle development using C. elegans as a model at Cornell University; Postdoctoral training in TOR signaling using budding yeast as a model at Pittsburgh University; Postdoctoral training in embryonic stem cell biology and reprogramming at University of Wisconsin-Madison.

Society Memberships
Organization Name Position Held Org Link
Genetics Society of America, GSA    http://www.genetics-gsa.org 
International Society for Stem Cell Research , ISSCR    http://www.isscr.org 

Research/Clinical Interest
Title
Molecular mechanisms of somatic cell reprogramming to pluripotency; self-renewal of pluripotent stem cells (PSC); Pluripotency; Epigenetics of PSC and reprogramming
Description
Molecular mechanisms of somatic cell reprogramming to pluripotency; self-renewal of pluripotent stem cells (PSC); Pluripotency; Epigenetics of PSC and reprogramming

Positions Available
Date Posted Position Title
8/8/2014  Research associate or PhD student positions available 
research on reprogramming, pluripotency, self-renewal and epigenetics   

Selected Publications 
Publication PUBMEDID
Kejin Hu. (2008). Homologous recombination and innocuous intron elimination. In Genetic Recombination Research Progress. Chapter 14, Pp. 323-333. Nova Science Publishers, Inc. ISBN: 978-1-6045-482-2   
Nirav M. Amin, Kejin Hu, David Pruyne, Dino Terzic, Anthony Bretscher & Jun Liu, (2007). A Zn-finger/FH2-domain containing protein, FOZI-1, acts redundantly with CeMyoD to specify striated body wall muscle fates in the Caenorhabditis elegans postembryonic mesoderm. Development, 134(1), 19-29.  17138663 
Nirav M. Amin, Kejin Hu, David Pruyne, Dino Terzic, Anthony Bretscher & Jun Liu, (2007). A Zn-finger/FH2-domain containing protein, FOZI-1, acts redundantly with CeMyoD to specify striated body wall muscle fates in the Caenorhabditis elegans postembryonic mesoderm. Development, 134(1), 19-29.  17138663 
Kejin Hu and Pak Chow Leung. (2007). Food digestion by cathepsin L and the digestion-related cell differentiation in shrimp hepatopancreas. Comparative Biochemistry and Physiology Part B, 146, 69-80.    
Kejin Hu, (2006). Intron exclusion and the mystery of intron loss. FEBS Letters, 580(27), 6361-6365.   17092501 
Kejin Hu & Pak Chow Leung, (2006). Complete, precise and innocuous loss of multiple introns in the currently intronless, active cathepsin L-like genes, and inference from this event. Molecular Phylogenetics and Evolution, 38, 685-696.
 
 
Ke-jin Hu, Pak-Chow Leung, (2004). Shrimp cathepsin L encoded by an intronless gene has predominant expression in hepatopancreas, and occurs in the nucleus of oocyte. Comparative Biochemistry and Physiology, Part B, 137(1), 21-33.    
Kran Suknuntha, Yuki Ishii, Kejin Hu, Jean Wang, Scott Swanson, Ron Stewart, James Thomson, Igor Slukvin. (2013) Induced pluripotent stem cell model of chronic myeloid leukemia revealed olfactomedin 4 as a novel therapeutic target in leukemia stem cells. Experimental Hematology, 41(8), S17.   
Kejin Hu, Kwok-Wing Yeung, Jinlian Hu, Kwok-ping Ho, (2004). Screening of fungi for chitosan producers, and copper adsorption capacity of fungal chitosan and chitosanaceous materials. Carbohydrate Polymers, 58 (1): 45-52.    
Ke-Jin Hu, Kwok-Wing Yeung, Kwok-Ping Ho, and Jin-lian Hu (1999). Rapid extraction of high-quality chitosan from mycelia of Absidia glauca, Journal of Food Biochemistry, 23, 187-196.   
Kejin Hu and Igor Slukvin (2013) Generation of transgene-free iPSC lines from human normal and neoplastic blood cells using episomal vectors. Methods in Molecular Biology, Pluripotent Stem Cells: Methods and Protocols. Vol. 997, pp. 163-176.   23546755 
Kejin Hu and Igor Slukvin (2013). Induction of pluripotent Stem cells from umbilical cord blood. Stem Cells: from biology to therapy. Vol. 1, Pp. 345-369.    
Kejin Hu and Igor Slukvin (2012) Induction of pluripotent Stem cells from umbilical cord blood. Encyclopedia of Molecular Cell Biology and Molecular Medicine: Stem Cells. 2nd edition, ed. Robert Meyers, Wiley-VCH, 1-25.    
Kejin Hu, Junying Yu, Kran Suknuntha, Shulan Tian, Karen Montgomery, Kyung-Dal Choi, Ron Stewart, James Thomson, Igor Slukvin, (2011). Efficient reprogramming of mononuclear cells from archived normal and neoplastic human bone marrow and cord blood with non-integrating episomal constructs. Blood, 117, e109-e119.  21296996 
Junying Yu, Kejin Hu, Kim Smuga-otto, Shulan Tian, Ron Stewart, Igor I Slukvin, James A Thomson, (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science, Vol. 324, 797-801  19325077 
Kejin Hu, (2014), Vectorology and factor delivery system in induced pluripotent stem cell reprogramming. Stem Cells and Development, 23(12): 1301-1315.   24625220 
Kejin Hu, (2014), All roads lead to induced pluripotent stem cells: the technologies of iPSC generation. Stem Cells and Development, 23(12) 1285-1300.
 
24524728 

Keywords
Reprogramming; embryonics stem cells; Induced pluripotent stem cells; pluripotency; epigenetics