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Faculty Detail    
Name SUMANTH D PRABHU
  
Campus Address THT 311 Zip 0006
Phone 205-934-3624
E-mail sprabhu@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Medicine  Med - Cardiovascular Disease Professor
Secondary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Professor
Center  Cell, Developmntl, & Integrative Biology  Ctr for Exercise Medicine Professor

Biographical Sketch 
Dr. Prabhu received a BS degree in Science from Penn State University and his MD degree from Jefferson Medical College in Philadelphia. He did internal medicine residency at the University of Pittsburgh and a cardiology fellowship at the University of Texas Health Science Center at San Antonio. He was a cardiology faculty there as well as at the University of Louisville, before his arrival to UAB as Director of Cardiovascular Disease. Dr. Prabhu serves on the Editorial Board of Circulation Research and is a member of the American Society for Clinical Investigation.

Research/Clinical Interest
Title
Mechanisms of cardiac remodeling and repair in heart failure
Description
We are actively studying fundamental mechanisms of pathological remodeling in the failing heart, with a particular focus on inflammatory pathways (tumor necrosis factor, nuclear factor-kappaB) and cell types (e.g., macrophages). We are also interested in the interplay between inflammatory signaling and cardiac stem cell-mediated repair in the failing heart. Our clinical studies examine the effects of mechanical support (ventricular assist devices) on forward and reverse remodeling in human heart failure.

Keywords
heart failure, ventricular remodeling, stem cells, inflammation, cardiac function

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