Back to Main

Faculty Detail    
Name EMMA PEREZ-COSTAS
 
Campus Address SC 865C Zip 0017
Phone 205-996-9374
E-mail epcostas@uab.edu
Other websites http://www.researchgate.net/profile/Emma_PEREZ-COSTAS/
http://goo.gl/V8rBR
http://community.frontiersin.org/people/EMMAPEREZ-COSTAS/22138
http://www.uab.edu/medicine/neurobiology/faculty/78-ecostas
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Psychiatry   Psych - Behavioral Neurobiology Assistant Professor
Secondary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Assistant Professor
Secondary  Neurobiology  Neurobiology Assistant Professor
Center  General Clinical Research Center  Comprehensive Neuroscience Center Assistant Professor

Graduate Biomedical Sciences Affiliations
Neuroscience 

Biographical Sketch 
-Bachelor in Science, Biology (1996). University of Santiago de Compostela, Spain
-Master in Science, Cell Biology (1998). University of Santiago de Compostela, Spain.
-PhD, Cell Biology/Neuroscience (2002). University of Santiago de Compostela, Spain.
-Postdoctoral Fellow (2003-2006), Maryland Psychiatric Research Center. University of Maryland, School of Medicine.
-Faculty Instructor (2006-2007), Maryland Psychiatric Research Center. University of Maryland, School of Medicine.
-Assistant Professor (2007-present), University of Alabama at Birmingham.

Society Memberships
Organization Name Position Held Org Link
AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE  REGULAR MEMBER  http://www.aaas.org 
ASOCIACION DE BIOLOGOS DE GALICIA (Galcian Biologists Association)  REGULAR MEMBER  http://www.biologosdegalicia.org 
FACULTY FOR UNDERGRADUATE NEUROSCIENCE  REGULAR MEMBER  http://www.funfaculty.org 
SOCIETY FOR NEUROSCIENCE  REGULAR MEMBER  http://www.sfn.org 

Research/Clinical Interest
Title
ASSISTANT PROFESSOR
Description
-The dopaminergic mesocortical pathway and its impact in cortical function in neurological and neuropsychiatric disorders.
-Characterization of novel animal models for the study of human brain pathology.
-Adaptation or development of new histological techniques.
-Development of the mesodiencephalic dopaminergic system

Funded Research:
12/2010-11/2015 Principal Investigator (MPI), Neuropathology of Dopamine Systems in Schizophrenia, funded by National Institutes of Mental Health (RO1MH066123)

People in the Lab
-Matthew W. Rice, Graduate Student, email:stvanek@uab.edu
-Ryan P. Lee, Undergraduate Student, Neuroscience and Science and Technology Honors Programs, UAB. email: panthera@uab.edu
-Kristen L. Smith, Undergraduate Student, Neuroscience and Science and Technology Honors Programs, UAB. email: kls93@uab.edu Watch Kristen explaining some of her work in the lab: Kristen explains work

Selected Publications 
Publication PUBMEDID
Gandy JC, Melendez-Ferro M, Bijur GN, Van Leuven F, Roche JK, Lechat B, Devijver H, Demedts D, Perez-Costas E*, Roberts RC* (2013) Glycogen synthase kinase-Beta;(GSK3-B) expression in a mouse model of Alzheimer's disease: A light and electron microscopy study. Synapse. 2013 Feb 7. doi: 10.1002/syn.21642. [Epub ahead of print]
[*Co-corresponding authors] 
23390016 
Melendez-Ferro M, Rice MW, Roberts RC, Perez-Costas E (2013) An accurate method for the quantification of cytochrome C oxidase in tissue sections. J Neurosci Methods. 2013 Jan 30. pii: S0165-0270(13)00030-7. doi: 10.1016/j.jneumeth.2013.01.010. [Epub ahead of print]  23376420 
Melendez-Ferro M, Rice MW, Roberts RC, Perez-Costas E (2012) Dual use of immunohistochemistry for film densitometry and light microscopy. J Neurosci Methods, 208(1):86-91  22579877 
Perez-Costas E, Melendez-Ferro M, Rice MW, Conley RR, Roberts RC (2012) Dopamine pathology in schizophrenia: Analysis of total and phosphorylated tyrosine hydroxylase in the substantia nigra. Front. Psychiatry 3:31. doi: 10.3389/fpsyt.2012.00031  22509170 
Rice MW, Roberts RC, Melendez-Ferro M, Perez-Costas E (2011) Neurochemical characterization of the tree shrew dorsal striatum. Frontiers in Neuroanatomy 2011;5:53.
 
21887131 
Barksdale KA, Perez-Costas E, Gandy CG, Melendez-Ferro M, Roberts RC, Bijur GN (2010) Mitochondria viability in mouse and human postmortem brain. FASEB Journal, 24(9): 3590-9  20466876 
Perez-Costas E, Gandy JC, Melendez-Ferro M, Roberts RC, Bijur GN (2010). Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain. PLoS One 5(1):e8911.  20111716 
Perez-Costas E, Melendez-Ferro M, Roberts RC (2010) Basal ganglia pathology in schizophrenia: dopamine connections and anomalies. Journal of Neurochemistry, 113(2):287-302  20089137 
Melendez-Ferro M, Perez-Costas E, Roberts RC (2009) A new use for long-term frozen brain tissue: Golgi impregnation. Journal of Neuroscience Methods, 176(2):72-7  18789970 
Perez-Costas E, Guidetti P, Melendez-Ferro M, Kelley JJ, Roberts RC (2008) Neuroleptics and animal models: feasibility of oral treatments monitored by plasma levels and receptor occupancy assays, The Journal of Neural Transmission,115(5):745-53  18193153 

Keywords
neuroanatomy, neuropathology, dopamine systems, neurobiology, neuronal development, neurological disorders, neuropsychiatric disorders

© 2008 University of Alabama at Birmingham. All rights reserved. DisclaimerAbout this SiteGraphic Design Created by UAB Web Communications.
Calendar Designed by Medical Education Information Services. To report problems with the site, email us at 
meis@uab.edu. Last Revision: February 15, 2012.
The UAB School of Medicine Mailing Address: 1530 3rd Avenue South, FOT 1203, Birmingham AL 35294-3412