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Faculty Detail    
Campus Address ACC 316 Zip 0011
Phone 205-975-7499
Other websites

Medical School  University of North Carolina Chapel Hill    1996  MD 
Graduate  University of North Carolina Hospital    1997  MD 
Residency  University of North Carolina     2002  Orthopedic Surgery 
Fellowship  Children's Hospital of Atlanta    2003  Pediatric Orthopedic Surgery 

Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Surgery   Surgery - Orthopaedic Associate Professor
Secondary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Associate Professor
Secondary  Pathology   Molecular & Cellular Pathology Assistant Professor
Center  Biomedical Engineering  Biomatrix Eng Regen Med (BERM) Ctr Associate Professor
Center  Center for Metabolic Bone Disease  Center for Metabolic Bone Disease Associate Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Associate Professor
Center  Nutrition Sciences   Nutrition Obesity Res Ctr (NORC) Associate Professor

Biographical Sketch 
University of North Carolina School of Medicine
M.D. with Honors, 1996

University of North Carolina at Chapel Hill
B.S. Biology with Distinction and Highest Honors, 1992

Vern Tolo Basic Science Paper Award - Recognizes outstanding basic science presentation at annual meeting of Pediatric Orthopaedic Society of North America, 2009.

St. Giles Young Investigator Award – Awarded by Pediatric Orthopaedic Society of North America to a promising young investigator in the field of Pediatric Orthopaedics, 2009.

Most outstanding teaching performance by a resident –
Musculoskeletal course for second year medical students, UNC School of Medicine, 1998

Fellowship, Pediatric Orthopaedic Surgery
Children’s Healthcare of Atlanta

Residency, Orthopaedic Surgery
UNC Hospitals
Research track

Research/Clinical Interest
I have two foci of basic science research. My principal interest has been investigating the role of the hypoxia inducible factor (HIF) pathway and angiogenesis in the skeleton. I am pursuing a line of investigation that angiogenesis drives osteogenesis, both during development and repair. I am using genetic mouse models and pharmacologic interventions to increase angiogenesis by targeting HIF. I have also identified additional HIF activating pro-angiogenic compounds that are under development. I have recently developed a new translational research interest in obesity and musculoskeletal health. I am pursuing both clinical studies and animal studies to examine musculoskeletal health (outcomes measures), injuries and mechanisms that predispose to injury or impair recovery. Additional clinical research interests include publications and presentations on limb and spine deformity, fractures, skeletal maturation, and musculoskeletal infections, and an ongoing randomized clinical trial comparing bracing styles for clubfeet.

HIF, angiogenesis, bone, obesity, fracture