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SAMUEL CORBIN CARTNER
RSB 220L Zip 0019
Genetics Chair Office
General Clinical Research Center
Ctr for Clinical & Translational Sci
As one of the clinical veterinarians in the Animal Resources Program my primary function is to assist other researchers in the selection of appropriate models and the proper acquisition and maintenance of healthy animals for their research. In addition, I assist researchers in experimental procedures and assure that all activities are acceptable according to the relevant regulations. My research interest is the genetic susceptibility to infectious disease. The model used in our laboratory is murine respiratory mycoplasmosis (MRM). Mycoplasmal pneumonia is commonly called the "walking pneumonia" in humans and represents a significant cause of disease and death. Our research group has shown that nonspecific defense mechanisms are primarily responsible for the prevention of infection and disease due to M. pulmonis in mice and that specific immune mechanisms exacerbate lung disease but decrease extrapulmonary dissemination. The primary focus of my research is to perform linkage analysis in mice to determine the number and chromosomal location of genes that influence the resistance to mycoplasmal pneumonia.
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