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Faculty Detail    
Name LISA M SCHWIEBERT
 
Campus Address MCLM 955 Zip 0005
Phone 205-934-3970
E-mail lschwieb@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Professor
Secondary  Cell Biology   Cell Biology Associate Professor
Secondary  Medicine  Med - Pulmonary/Allergy/Critical Care Associate Professor
Center  Arthritis & Musculoskeletal Diseases Center  Arthritis & Musculoskeletal Diseases Center Professor
Center  Center for Biophysical Sciences/Engineering  Center for Biophysical Sciences/Engineering Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Professor
Center  Cell, Developmntl, & Integrative Biology  Ctr for Exercise Medicine Professor
Center  Cystic Fibrosis Research Center  Cystic Fibrosis Research Center Professor
Center  Medicine  Lung Health Center Professor

Graduate Biomedical Sciences Affiliations
Cell, Molecular, & Developmental Biology 
Cellular and Molecular Biology Program 
Immunology 
Integrative Biomedical Sciences 
Medical Scientist Training Program 
Pathobiology and Molecular Medicine 

Biographical Sketch 
Lisa M. Schwiebert received a BS degree in Chemistry from Bates College in 1986 and a PhD in Biochemistry from Dartmouth College in 1993. After completing her postdoctoral training in Clinical Immunology at Johns Hopkins University, she was appointed as an instructor in the Department of Medicine at Johns Hopkins University. Dr. Schwiebert joined the faculty of the Department of Physiology and Biophysics at UAB in 1997 as an Assistant Professor and was promoted to Associate Professor with tenure in 2003; she was promoted to Professor in 2013. In 2007, she was appointed Associate Dean for Postdoctoral Education.

Society Memberships
Organization Name Position Held Org Link
American Association of Immunologists  member   
American College of Sports Medicine  member   
American Physiological Society  member   
American Society for Biochemistry and Molecular Biology  member   
American Thoracic Society  member   

Research/Clinical Interest
Title
Airway inflammation; lung function; asthma and exercise
Description
The main focus of the laboratory is to understand the physiologic mechanisms that underlie lung immunity through molecular, whole animal, and translational approaches.

Selected Publications 
Publication PUBMEDID
Dugger, K, Lowder, T, Tucker, T, and L.M. Schwiebert. Epithelial cells as immune effector cells: the role of CD40. Sem. Immunol., In press, 2009.  19628407 
Hewitt, M., Estell, K., Davis, I., and L.M. Schwiebert. Repeated bouts of moderate intensity aerobic exercise reduce airway reactivity in a murine asthma model. Am J Respir Cell Mol Biol., In press, 2009.  19423772 
Hewitt, M., Creel, A., Estell, K., Davis, I., and L.M. Schwiebert. Acute exercise decreases airway inflammation, but not responsiveness, in an allergic asthma model. Am J Respir Cell Mol Biol., 40:83-89, 2009.  18635813 
Lowder, T., Dugger, K., Deshane, J., Estell, K., and L.M. Schwiebert. Repeated Bouts of Aerobic Exercise Enhance Regulatory T Cell Responses in a Murine Asthma Model. Brain Behav. Immunol., In press, 2009.   
Tucker, T and LM Schwiebert. CD40 ligation decreases its protein half-life at the cell surface. Eur. J. Immunol. 38:864-869, 2008.   
Pastva, A., Estell, K., Schoeb, T., and L. M. Schwiebert. RU486 blocks the effects of exercise in a
murine model of allergen-induced pulmonary inflammation. Brain Beh. Immunol. 19:413-422, 2005. 
 
Pastva, A., Atkinson, T. P., Schoeb, T., Estell, K., and L. M. Schwiebert. Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic responses. J. Immunol. 172:4520-4526, 2004.   
Estell, K., Braunstein, G., Collawn, J., and L. M. Schwiebert. Plasma membrane CFTR regulates RANTES expression via its C-terminal PDZ-interacting domain. Mol. Cell. Biol. 23:594-606, 2003.   
Propst, S. M., Estell, K., and L. M. Schwiebert. CD40-mediated activation of NF-kB in airway epithelial cells. J. Biol. Chem., 277:37054-63, 2002.   
Schwiebert, L. M., Rice, W. C., Kudlow, B. A., Taylor, A. L., and E. M. Schwiebert. Extracellular ATP signaling and P2X purinergic receptor channels in primary human vascular endothelia. Amer. J. Physiol. (Cell), 282:C289-301, 2002.   
Propst, S.M., Estell, K., Denson, R., Rothstein, E., and L. M. Schwiebert. CD40 expression and function in human airway epithelia. J. Immunol., 165:2214-2221, 2000.   
Schwiebert, L. M., Estell, K., and S.M. Propst. Chemokine expression in CF airway epithelia: implications for the role of CFTR in RANTES expression. Amer. J. Physiol (Cell), 276:C700-710, 1999.